An Assessment of Hepato-Protective Activity of Psidium guajava Fruit Extract against Hepatic Injured Rodent Model
Md. Abdullah Hil Baky Rupak, F. M. Sharifuzzaman Shohan, Juliana Aditi Baroi, Md. Rahmat Ullah, Md. Mustafiz Chowdhury, Bornila Mehjabin, Puja Bhowmik, Nur-Neasha Dolon, Rafat Tashin
Asian Journal of Medical Principles and Clinical Practice · pp. 240–245 · Published 7 Oct 2023
Abstract
Herbal remedies are the art or practice of using herbs and herbal medicines to maintain health and prevent, treat, or cure sickness. The lipid profiles of Psidium guajava extract were studied in rats. In the case of Serum glutamic pyruvic transaminase (SGPT) and serum glutamic-oxaloacetic transaminase (SGOT), only the high dose produced statistically significant (p<0.05) outcomes as compared to the negative control group. At low, medium, and high dosages, creatinine levels decreased statistically significant (p<0.05). However, none of the dosages in case of urea produced statistically significant (p<0.05) effects. Only at high dosages did total cholesterol levels reduce statistically significantly (p<0.05) when compared to the negative control group. Only at high doses did High Density Lipoprotein (HDL) levels improve statistically significantly (p<0.05). High and medium dosages of Low Density Lipoprotein (LDL) significantly (p<0.05) reduce the quantity in the blood. Triglyceride levels were reduced only at high dosages as compared to the negative control group. These discoveries may benefit those suffering from liver disorder.
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