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Research Article Open access CC BY 4.0

Diagnosis of Bovine Mastitis and Its Advanced Therapeutic Strategies: A Review

Govina Dewangan, Nitesh Kumbhakar

Microbiology Research Journal International · pp. 43–53 · Published 12 Jan 2026

10.9734/mrji/2026/v36i11694

Abstract

Mastitis is a major disease causes serious economic losses to farmer and adversely impact at national level. Due to the effect of mastitis body condition of animal is highly deteriorate along with drop in milk production. Sometimes it resulted in expelling the cow from herd. The composition of milk is seriously altered with the presence of high number of bacteria. Mastitis is a multifactorial disease caused by a variety of pathogenic organisms including bacteria, fungi and yeasts which cause inflammation and sometime results in udder fibrosis. In this review we will discuss the diagnosis of mastitis and some alternative advanced therapeutic approaches. Till date antibiotics are still in use for therapeutic purpose but due to rise in incidence of multi drug resistance bacteria, alternative therapeutic search becomes need of this hour. Homeopathic treatment of udder and animal, injection of oxytocin, cytokine therapy, natural products, vitamin E therapy, cytokine therapy bacteriocin, bacteriophage therapy are now in pipeline as a alternate therapeutic agent to curb the bovine mastitis. Overall, successful management of bovine mastitis depends on a multidisciplinary and an integrated strategy combining therapeutic, clinical, hygienic, and management intervention.

Alternative therapy bacteriocin bacteriophage intra mammary mastitis Somatic cell count

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