Recognizing Paradigm Instability in Theories of Carcinogenesis
Journal of Advances in Medicine and Medical Research · pp. 1149–1163 · Published 8 Nov 2013
10.9734/BJMMR/2014/6855Abstract
The dominant view that cancer arises from successive mutations in somatic cells is so unquestioned that accumulating challenges from experimental and observational results are rarely addressed in the scientific literature. Based on these challenges, we argue that the scientific understanding of carcinogenesis has entered a period of paradigm instability. New research directions are therefore needed.
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