Recent Developments and Biological Activities of 5-Oxo-Imidazolones Derivatives: A Review
N. Yellasubbaiah, V. Velmurugan, B. Nagasudha
Journal of Pharmaceutical Research International · pp. 287–305 · Published 30 Sep 2021
10.9734/jpri/2021/v33i45A32746Abstract
Heterocyclic compounds are essential primary units for both the synthetic and natural starting points. 5-oxo-imidazolone is a 5-member ring system that contains 3 carbons and 2 nitrogens that are arranged at 3 and 1 positions, and ─C═O at the 5th position of the ring. 5-oxo-imidazolone is known as a privileged molecule because of its all biological potency. This biological property increased the attention of many investigators to analyze this ring system and expose several activities. The present review aims to outline the various activities reported on the synthesis and the biological potencies of 5-oxo-imidazolone derivatives. 5-oxo-imidazolone is an important pharmacophore in modern drug discovery.
Cited by 3
Jan Chasák, Ignacy Janicki, Lucie Brulíková · European Journal of Medicinal Chemistry · 2025
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