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Research Article Open access CC BY 4.0

Proanthocyanidins and Dental Health: Uncovering the Benefits

Rajeshwari Baskar, Daya Srinivasan

Journal of Pharmaceutical Research International · pp. 65–79 · Published 25 Jul 2024

10.9734/jpri/2024/v36i87559

Abstract

Proanthocyanidins (PAs) are a subclass of flavonoids that are widely distributed in different plant sources and have attracted interest due to their potential health advantages, especially in maintaining dental health. The purpose of this review is to better understand the properties and applications of proanthocyanidins in maintaining dental health. Proanthocyanidins have excellent antibacterial, anti-inflammatory, and antioxidant qualities that are vital for preventing oral illnesses such oral cancer, periodontal disorders, and dental caries. Furthermore, PAs have demonstrated efficacy in augmenting salivary flow, and encouraging tooth enamel remineralization. Moreover, proanthocyanidins are low in toxicity and have good biocompatibility, which makes them good choices for adding to a variety of mouthwash, toothpaste, and dental materials. Their minimal side effects and natural source make them even more desirable for use in oral health interventions. However, Further research is needed to fully investigate their therapeutic potential and optimize their use in preventive and treatment methods for oral diseases.

Proanthocyanidins remineralization oral health dental caries grape seed extract

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