Prevalence of Extended-Spectrum β-Lactamase and Antimicrobial Susceptibility Pattern of Clinical Isolates of Pseudomonas in Tertiary Care Centre of Kutch

Abstract

Aim: The current research was performed with an aim to discover the prevalence of ESBL producing P. aeruginosa and also to provide as a direct for doctors administration subjects by executing suitable infection control events as well as inventing an efficient antibiotic policy. Materials and Methods: The current research was performed in the Department of Microbiology at Gujarat Adani Institute of Medical Science, Bhuj, Kutch, Gujarat over a period for one year. All 250 isolates of Pseudomonas aeruginosa acquired from different clinical samples established in microbiology laboratory from IPD & OPD were incorporated in the research. Different clinical specimens established in our laboratory were coursed and Pseudomonas aeruginosa was recognized as apiece normal microbiological method. All isolates were subjected for ESBL screening test. Antimicrobial susceptibility test was performed by Kirby. Results: Highest samples established from middle age group (30- 50). Out of 250 isolates, 177 (70.7%) isolates of Pseudomonas aeruginosa demonstrated zone of inhibition≤ 22 mm for Ceftazidime. All ESBL positive Pseudomonas aeruginosa isolates demonstrated elevated confrontation to ciprofloxacin 43 (91.04%), Gentamicin 34 (72.3%) and tobramycin 33 (70.21%). Conclusion: The majority of isolates were from hospitalized subjects which point out additional probability of their nosocomial predominance.