Plasma Levels of Connective Tissue Growth Factor in Children with Congestive Heart Failure
Riham Mahmoud Wagieh, Ahmed Hamdy Shabana, Hesham Mohammed Elserogy, Amr Mohamed Zoair
Journal of Advances in Medicine and Medical Research · pp. 110–116 · Published 15 Feb 2020
10.9734/jammr/2020/v32i130358Abstract
Objectives: Assessment of plasma level of connective tissue growth factor in congestive heart failure children, assessment of its diagnostic and prognostic role and correlate its level with clinical and echocardiographic assessment of congestive heart failure. Methods: Connective tissue growth factor level in the plasma was measured in 40 children; 20 of them have congestive heart failure, and 20 are healthy then, correlated with clinical parameters. Results: The diagnostic and prognostic value of it was evaluated. We compared its levels in both patients and healthy children. We found that connective tissue growth factor level was significantly increased in diseased children. Fractional shortening and ejection fraction correlated negatively with the plasma level of connective tissue growth factor. Heart rate, respiratory rate and calibrated integrated backscatter correlated positively with connective tissue growth factor. Connective tissue growth factor was significantly correlated with the class of heart failure according to Ross classification. Conclusions: Plasma connective tissue growth factor has a promising diagnostic and prognostic value as a biomarker for congestive heart failure in children with high sensitivity and specificity.
Cited by 0
No indexed citations yet.
Related research
- A Potential Role of Fructose to Modulate Fibroblast Growth and Expression of Connective Tissue Growth Factor In vitro — shares topic coverage
- The First Six Registered Pediatric Cases with COIVID-19 in Libya: A Case Study — shares topic coverage
- Intrapulmonary Administration of Autologous Bone Marrow Derived Mononuclear Cells in Congenital Heart Disease Complicated by Pulmonary Arterial Hypertension: A Case Report — shares topic coverage
- Home Injury Prevention in Children: Attitude & Awareness of the Caregivers at King Abdul-Aziz Medical City - Pediatric Emergency, Riyadh, KSA — shares topic coverage
- What Can Physicians Propose to Help Children with Aspecific Cough? Review of the Literature — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.