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Research Article Open access CC BY 4.0

Antibiotic/Antibacterial activity of Vitex negundo, Duranta repens, Acorus calamus and Piper nigrum

Burhan M. Padder, Shagufta Yasmeen, Mudasar Ganaie

Biotechnology Journal International · pp. 16–22 · Published 14 Jan 2015

10.9734/BBJ/2015/14534

Abstract

Antibiotic/Antibacterial activity of Vitex negundo, Duranta repens, Acorus calamus and Piper nigrum Plants produce a diverse nature of secondary metabolites having different biological activity. Some of these chemicals exhibit antimicrobial activity. In the present study the plant extracts of Vitex negundo, Duranta repens, Acorus calamus and Piper nigrum were tested individually as well as synergistically for antibiotic/ antibacterial activities. It was found that the plant extract of V. negundo was most effective against both S. mutans MTCC 890(MIC value 0.37) and P. aeruginosa MTCC 0741 (MIC value 0.75) than other three extracts of D. repens, P. nigrum, A. calamus whereas the plant extract of P. nigrum was least effective against both S. mutans MTCC 890(MIC value 3.12) and P. aeruginosa MTCC 0741(MIC value 6.25).

Antimicrobials plant extracts secondary metabolites individual synergistic activity

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