Skip to content
Research Article Open access CC BY 4.0

Phytochemical Screening, GC-MS Analysis and Antioxidant Activity of Three Medicinal Plants From Nigeria

Ezekwe Ahamefula S., Ordu Kenneth S., Oruamabo Ralphael S.

Asian Journal of Applied Chemistry Research · pp. 14–26 · Published 7 Aug 2020

10.9734/ajacr/2020/v6i330162

Abstract

Phytochemical screening, GC-MS analysis and antioxidant activity of some medicinal plants were investigated using standard methods. Leaves of Gongronema latifolium, Petrocarpus mildbraedii, and Piper guineense plants were prepared properly and used in the entire study. Results of phytochemical screening for the plants revealed the presence of tannins, saponins, alkaloids, phenolic compounds, reducing sugars amongst others at different concentrations. Results of GC-MS analysis for G.latifolium showed a total of thirty-three compounds of which Cyclohexano, 2-l(methlaminomethyl)-trans had the highest retention time, squalene had the highest molecular weight and phytol had the highest peak area. GC-MS result for P.mildbraedii revealed a total of twenty-three of which Acatamide,2,2,2-trichloro- had the highest retention time, Erucic acid had the highest molecular weight whereas n-Hexadecanoic acid the highest peak area. Only ten compound were observed in P.guineense of  which Ethyl (3-hydroxyphenyl) carbamate had the highest retention time, Benzaminde, N-(4,5-dichloro-1,3-benzothiazol-2yl)-3,5-dimethoxy- had the highest molecular weight and Benzene, 1,2,3-trimethoxy-5-(2-propenyl)- has the highest peak area in P. guineense. The antioxidant activity of the plant extracts as assessed, followed the order P.guineense > G.latifolium> P. mildbraedii in comparative with ascorbic acid used as the control. The observed compounds become very important when the usefulness of these plants as medicinal plants are considered. They could as well be behind the antioxidant property of the plants in this study. This study has revealed the phytochemical screening, GC-MS analysis and antioxidant activity of some medicinal plants.

Antioxidants activity GC-MS analysis phytochemicals medicinal plants.

References (36)

  1. 1 ASCORBATE AND GLUTATHIONE: Keeping Active Oxygen Under Control [DOI]
  2. 2 Reactive Oxygen Species, Oxidative Damage, and Antioxidative Defense Mechanism in Plants under Stressful Conditions [DOI]
  3. 3 Medicinal plants and traditional medicine in Africa
  4. 4 Medicinal Plants and Traditional Medicine in Africa [DOI]
  5. 5 Biochemistry of Plant Volatiles [DOI]
  6. 6 Higher plant terpenoids: A phytocentric overview of their ecological roles [DOI]
  7. 7 Tannins: Current knowledge of food sources, intake, bioavailability and biological effects [DOI]
  8. 8 Fruit and Vegetable Consumption, Nutritional Knowledge and Beliefs in Mothers and Children [DOI]
  9. 9 Phytochemistry of Medicinal Plants [DOI]
  10. 10 Free radical biology and medicine [DOI]
  11. 11 How to characterize an antioxidant: an update [DOI]
  12. 12 Red wine polyphenols influence carcinogenesis, intestinal microflora, oxidative damage and gene expression profiles of colonic mucosa in F344 rats [DOI]
  13. 13 The Useful Plants of West Tropical Africa [DOI]
  14. 14 Medicinal Plants of the World [DOI]
  15. 15 Phytochemistry of medicinal plants [DOI]
  16. 16 Chemical composition and antibacterial activity of Gongronema latifolium [DOI]
  17. 17 Evaluation of antibacterial activity of Pisidium guajava and Gongronema Latifolium [DOI]
  18. 18 Phytochemical, vitamin and proximate composition of Dacryodes edulis fruit at different stages of maturation
  19. 19 Structural root form and fine root distribution of some woody species evaluated for agroforestry systems [DOI]
  20. 20 Effect of Caffeine on Some Selected Biochemical Parameters Using Rat Model [DOI]
  21. 21 Toxic effect of carica papayabark on body weight, haematology, andsome biochemical parameters
  22. 22 Toxicity Evaluation of the Aqueous Stem Extracts of Senna alata in Wistar Rats [DOI]
  23. 23 Chemical profile of an anti-malarial concoction "Udu" used in Umunchi autonomous community in Isiala Mbano L.G.A of Imo State, Nigeria
  24. 24 A review on Gongronema latifolium (Utasi): A novel antibiotic against Staphylococcus aureus related infections
  25. 25 Evaluation of nutritional, anti-nutritional and some biochemical studies on Pleurotus squarrosulus (Mont.) singer using rats [DOI]
  26. 26 Nutrient composition of "Nduduagworagwo", a traditional food of Akokwa people in Ideato North L.G.A of Imo State, Nigeria.
  27. 27 Effect of Solanum Macrocarpon Fruit on Haematology, Hepatic and Renal Function [DOI]
  28. 28 Nutritional, Phytochemical and Sensory Evaluation of “Mberiagworagwo” Traditional Food of Uruagunnewi People in Anambra State, Nigeria [DOI]
  29. 29 Effect of ethanolic leaf extract of Vinca major L. on biochemical parameters and glucose level of alloxan induced diabetic rats [DOI]
  30. 30 Biochemical effects of drinking Terminalia catappa Linn. decoction in Wistar rats [DOI]
  31. 31 Phytonutrients and antinutrients screening of D. edulis fruits at different maturation stages.
  32. 32 EFFECT OF "UDU", AN ANTIMALARIAL HERBAL PREPARATION ON VISCERAL ORGAN WEIGHT AND BLOOD LIPID PROFILES IN WISTAR RATS
  33. 33 Effect of Seasonal Water Fluctuation of a Water Body on Antioxidant Activity of Selected Plants of Lower Phylum (A Case Study of Nche stream)
  34. 34 TOXICITY OF SOME PLANTS IMPLICATED AS POISONS IN NIGERIAN ETHNOMEDICINE TO RATS [DOI]
  35. 35 Journal of Pharmacognosy and Phytochemistry [DOI]
  36. 36 Journal of Chemical and Pharmaceutical Research, 2015, 7(7):933-939

Cited by 5

Anti-obesity activities of n-hexane fraction of Pterocarpus mildbraedii leaves on obese male rats

Sarah A. AKANDE, Uju D. ILIEMENE, Gideon A. GYEBI · Notulae Scientia Biologicae · 2025

Investigation of the pharmacological properties and antioxidant activity of Curcuma longa. L

Fouad EL Mansouri, Hammadi El Farissi, Fadoua Asraoui · AIP Conference Proceedings · 2021

Showing 2 of 5 known citations — external sources report more than can currently be individually listed.

Related research

Article metrics

Real usage data collected on this platform.

18

Page views

0

PDF downloads

0

Outbound clicks

5

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.