Phytochemical Screening and Polyphenolic Contents of Dialium dinklagei and Diospyros monbuttensis, Two Ivorian Medicinal Plants Used to Treat Malaria
Tuo Karim, Béourou Sylvain, Touré André Offianan, Ouattara Karamoko, Silué Kigbafori Dieudonné, Tano Konan Dominique, Adagba Marius, Koffi David, Yao Serge Stephane, Djaman Allico Joseph, Coulibaly Adama
Journal of Advances in Medical and Pharmaceutical Sciences · pp. 144–153 · Published 16 Jan 2015
10.9734/JAMPS/2015/13779Abstract
Introduction: Malaria is a deadly parasitic infection in its severe form. It is caused by an endoparasite protozoan transmitted by a mosquito vector. Despite considerable efforts to eradicate it, this endemic disease remains a public health problem because of its high frequency, severity and the consequences it generates. Furthermore, the existing treatments are increasingly ineffective; it is therefore urgent to find new anti-malarial drugs. Objective: From the phytochemical screening and the determination of the polyphenolic content of Dialium dinklagei and Diospyros monbuttensis used in traditional medicine in Côte d'Ivoire to treat malaria, we identified families of chemical compounds that can guide us towards pharmacological studies. These studies allow us to identify new molecules which could be a possible alternative antimalarial reference used today because of their effectiveness in treating malaria. Materials and Methods: From Dialium dinklagei and Diospyros monbuttensis, we obtained extracts decoction and hexane extracts, methanolic and aqueous extraction after three solvents of increasing polarity (n-hexane, methanol, water), respectively. The crude extracts obtained were tested for chemical identification of groups that may be the basis of the expected therapeutic effects. Moreover, the decoction and methanol extracts were used to determine the polyphenolic compounds. Results: The results vary from one plant species to another and from one sample to another. Abundant presence of alkaloids in all samples and an absence of steroids in other extract except decoction extract of Diospyoros monbuttensis were observed. Therefore, the other chemical groups are present in all plants in varying proportions but depending on the mode of extraction. A higher content of phenols and tannins in Dialium dinklagei over Diospyros monbuttensis was observed. However, the content of flavonoids of Dialium dinklagei is relatively lower compared to that observed in Diospyros monbuttensis. Conclusion: The overall results of the phytochemical screening and polyphenolic content would partly explain the traditional healers’ infatuation to these plants as antimalarials.
References (24)
- 1 Estimation of total flavonoid content in propolis by two complementary colometric methods [DOI]
- 2 Phenolic content and antioxidant activity of olive extracts [DOI]
- 3 High Molecular Weight Plant Polyphenolics (Tannins) as Biological Antioxidants [DOI]
- 4 Analysis of condensed tannins using acidified vanillin [DOI]
- 5 Dietary Polyphenols and Their Biological Significance [DOI]
- 6 Evaluation of antioxidant capacity and total phenolic content of different fractions of selected microalgae [DOI]
- 7 Saponins from Edible Legumes: Chemistry, Processing, and Health Benefits [DOI]
- 8 Evaluation of the chemical composition of two Nigerian medicinal plants
- 9 Plant active components – a resource for antiparasitic agents? [DOI]
- 10 Oxygen species scavenging activity of phenolic extracts from hawthorn fresh plant organs and pharmaceutical preparations.
- 11 Review article number 134 pharmacology and chemotaxonomy of diospyros [DOI]
- 12 A review of the medicinal potentials of plants of the genus Vernonia (Asteraceae) [DOI]
- 13 Ethnomedicinal plants used by the valaiyan community of piranmalai hills (reserved forest), tamilnadu, India. A pilot study [DOI]
- 14 Modelling of solid-liquid extraction process of total polyphenols from soybeans [DOI]
- 15 Chemical composition and antioxidant properties of mature and baby artichokes (Cynara scolymus L.), raw and cooked [DOI]
- 16 In vitro studies on the sensitivity pattern of Plasmodium falciparum to anti-malarial drugs and local herbal extracts [DOI]
- 17 Legumes of Africa. A Check-List [DOI]
- 18 Resistance of proline-containing peptides to ruminal degradation in vitro [DOI]
- 19 Evaluation in vitro of antiplasmodial activity of ethanolic extracts of Funtumia elastica, Rauvolfia vomitoria and Zanthoxylum gilletii on Plasmodium falciparum isolates from Côte-d'Ivoire.
- 20 Ethnobotanical Utilization and Conservation of Chewing Sticks Plants Species in Ekiti State, Nigeria [DOI]
- 21 In-vitro studies on the sensitivity pattern of Plasmodium falciparum to antimalarial drugs and local herbal extracts [DOI]
- 22 Savoir-faire des populations locales des taxons du Jardin Botanique de Bingerville, Côte d’Ivoire [DOI]
- 23 ANTIMICROBIAL ACTIVITY OF CRUDE EXTRACTS OF DIOSPYROS MONBUTTENSIS (FAM: EBENACEAE) ROOT AND STEM BARKS [DOI]
- 24 Connaissances, attitudes et pratiques des tradipraticiens de la sante de la ville d'Abidjan sur le paludisme
Cited by 9
Zineb Timizar, Khalida Boutemak, Amel Hadj Ziane-Zafour · Separations · 2024
Zineb Timizar, Amel Hadj Ziane Zafour, Ibtessem Rahim · Euro-Mediterranean Journal for Environmental Integration · 2026
Showing 2 of 9 known citations — external sources report more than can currently be individually listed.
Related research
- ABO Blood Groups and Malaria Prevalence in a Referral Hospital in Nigeria — shares topic coverage
- Prevalence of Malaria among Pregnant Women and Children Under Five Years in Abi Local Government Area, Cross River State, Nigeria — shares topic coverage
- A Study on Relationship of Thrombocytopenia and Likelihood of Severe Malaria in Patients Admitted With Malaria in a Tertiary Care Hospital of Dakshina Kannada — shares topic coverage
- Platelet Alteration in Plasmodium vivax Malaria Patients in Thailand — shares topic coverage
- Patients’ Perception of Health Care Services in Malaria Endemic Area in Mali: Villages with Health Care Services Versus villages Without Health Care Services — shares topic coverage
Article metrics
Real usage data collected on this platform.
62
Page views
0
PDF downloads
39
Outbound clicks
9
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.