Phytochemical Composition, Medicinal Applications, and Pharmacological Insights: A Comparative Review of Rauvolfia serpentina and Rauvolfia tetraphylla
Sapugaskandage Shenya, Dinara Sendanayake, Sohani Medis, Niluka Dlirukshi
Asian Plant Research Journal · pp. 46–55 · Published 20 Jan 2025
10.9734/aprj/2025/v13i1292Abstract
Aims: This review article aims to compare the phytochemical profile, therapeutic potential and pharmacological activities of Rauvolfia serpentina and Rauvolfia tetraphylla. Scope of Review: Review data from published literature and assess about phytochemicals, therapeutic applications and efficacy of Rauvolfia serpentina and Rauvolfia tetraphylla against microorganisms and inflammation comparatively. Methodology: Research papers and review articles on Rauvolfia serpentina and Rauvolfia tetraphylla were collected and analyzed about phytochemicals, medicinal uses, antibacterial and inflammatory properties. Summary of Findings: Rauvolfia serpentina and Rauvolfia tetraphylla have many similarities in its phytochemistry such as alkaloids like Reserpine, Ajmaline. They have been used to treat similar diseases and illness conditions like hypertension, psychotic disorders and snake bites. Conclusion: According to the findings, due to endangered status of Rauvolfia serpentina, Rauvolfia tetraphylla can be used as an ideal substitute and can be used for developing novel antimicrobial and anti-inflammatory drugs with mild side effects. Further investigations are necessary to determine their efficacy.
References (20)
- 1 Medicinal plants: Traditions of yesterday and drugs of tomorrow [DOI]
- 2 Phytochemical analysis of some medicinal plants
- 3 A review of modern and conventional extraction techniques and their applications for extracting phytochemicals from plants [DOI]
- 4 In vitro anti-inflammatory activity of Ficus racemosa L. bark using albumin denaturation method [DOI]
- 5 Genus Rauvolfia: A review of its ethnopharmacology, phytochemistry, quality control/quality assurance, pharmacological activities and clinical evidence [DOI]
- 6 Antimicrobial activity of Rauvolfia tetraphylla and Physalis minima leaf and callus extracts [DOI]
- 7 Quantitative Determination of Reserpine, Ajmaline, and Ajmalicine in Rauvolfia serpentina by Reversed- Phase High-Performance Liquid Chromatography [DOI]
- 8 Rauvolfia serpentina L. Benth. ex Kurz.: Phytochemical, Pharmacological and Therapeutic Aspects
- 9 A Comparative Antibacterial, Antioxidant, and Antineoplastic Potential of Rauwolfia serpentina (L.) Leaf Extract with Its Biologically Synthesized Gold Nanoparticles (R-AuNPs) [DOI]
- 10 Quantification of reserpine content and antibacterial activity of Rauvolfia serpentina (L.) Benth. ex Kurz [DOI]
- 11 Inhibition of fatty acid amide hydrolase by kaempferol and related naturally occurring flavonoids [DOI]
- 12 Evaluation of Antibacterial Activity of Endemic Jeffreycia zeylanica Plant Found in Sri Lanka [DOI]
- 13 A REVIEW ON POTENTIAL BIOACTIVE CHEMICAL FROM RAUWOLFIA SERPENTINA: RESERPINE [DOI]
- 14 Isolation and Extraction of flavonoid from the leaves of Rauwolfia serpentina and evaluation of DPPH-scavenging antioxidant potential [DOI]
- 15 Optimization of Anti-Inflammatory Activity of Rauvolfia tetraphylla L. Crude Extracts Using Response Surface Methodology [DOI]
- 16 Sacred Trees of India: Traditional Approach towards Plant Conservation [DOI]
- 17 In vitro Anti-inflammatory Activity of Endemic Artocarpus nobilis Thw Found in Sri Lanka [DOI]
- 18 Investigation of anti-inflammatory activity of Rauvolfia tetraphylla using in vitro protein denaturation assay [DOI]
- 19 Green synthesis, Characterization of Silver Nanoparticles and Antimicrobial Activity using Rauvolfia tetraphylla L. [DOI]
- 20 Neuro-therapeutic effect of Rauvolfia serpentina (Sarpagandha/ Ekaweriya); A review [DOI]
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