Skip to content
Research Article Open access CC BY 4.0

Pharmacovigilance in Cameroon: Past, Present and Future Developments in Unlocking the Drug Development Process

Estella Achick Tembe Fokunang, Bruna Njeba, Marie Jose Essi, Rose Ngono Abondo, Banin Andrew Nyuki, Lovet Benyella Fokunang, Nubia Kaba, Marie-Thérèse Abena Ondoua, Ralf Duerr, Charles Ntungwen Fokunang

Journal of Advances in Medical and Pharmaceutical Sciences · pp. 21–44 · Published 5 Dec 2020

10.9734/jamps/2020/v22i930192

Abstract

The drug discovery and development processes are designed to guarantee that drugs are efficacious, nontoxic and of high standards of quality for human consumption. However, patient’s population with access to drugs at approval is only a fraction of the final target population. Therefore, a thorough understanding of the safety of medicines is generally only achieved after the marketing authorization of the drug, followed by pharmacovigilance or post marketing surveillance. Pharmacovigilance (PHV) is defined by WHO as “the science and activities that deals with the detection, assessment, understanding and prevention of the adverse drug reactions or any other possible drug-related interactions”. Health professionals, patients, drug manufacturers and drug regulatory authorities are therefore highly involved in the practice of PHV. Cameroon imports 95 % of drugs and health care products. Therefore, an effective mastery of the knowledge, attitude and practice of PHV will help to elaborate the development of our pharmacovigilance systems. This paper gives an overview of pharmacovigilance in Cameroon for unlocking the drug development process focusing on the past, present and future.

Pharmacovigilance Drug discovery development Cameroon.

References (28)

  1. 1 Adverse drug reactions: definitions, diagnosis, and management [DOI]
  2. 2 Under-Reporting of Adverse Drug Reactions [DOI]
  3. 3 Thalidomide‐induced teratogenesis: History and mechanisms [DOI]
  4. 4 Clinically relevant drug interactions with antiepileptic drugs [DOI]
  5. 5 Proposal for a New Tool to Evaluate Drug Interaction Cases [DOI]
  6. 6 Impact of poor-quality medicines in the ‘developing’ world [DOI]
  7. 7 The Gell–Coombs classification of hypersensitivity reactions: a re-interpretation [DOI]
  8. 8 Pharmacovigilance in resource-limited countries [DOI]
  9. 9 Pharmacovigilance: An Overview [DOI]
  10. 10 Adverse Drug Reaction Reporting in Africa and a Comparison of Individual Case Safety Report Characteristics Between Africa and the Rest of the World: Analyses of Spontaneous Reports in VigiBase® [DOI]
  11. 11 Medicines Regulation in Africa: Current State and Opportunities [DOI]
  12. 12 Estimated Under-Five Deaths Associated with Poor-Quality Antimalarials in Sub-Saharan Africa [DOI]
  13. 13 Under-reporting of adverse drug reactions: A challenge for pharmacovigilance in India [DOI]
  14. 14 Pharmacist’s knowledge, practice and attitudes toward pharmacovigilance and adverse drug reactions reporting process [DOI]
  15. 15 A Review of Pharmacovigilance [DOI]
  16. 16 Spurious and counterfeit drugs: a growing industry in the developing world [DOI]
  17. 17 Pharmacovigilance in perspective: drug withdrawals, data mining and policy implications [DOI]
  18. 18 Pediatric Drug Safety Surveillance in FDA-AERS: A Description of Adverse Events from GRiP Project [DOI]
  19. 19 Treatment outcomes in a safety observational study of dihydroartemisinin/piperaquine (Eurartesim®) in the treatment of uncomplicated malaria at public health facilities in four African countries [DOI]
  20. 20 A national approach to pharmacovigilance: The case of India as a growing hub of global clinical trials [DOI]
  21. 21 Pharmacovigilance and global HIV/AIDS [DOI]
  22. 22 A situational analysis of pharmacovigilance plans in the Global Fund Malaria and U.S. President's Malaria Initiative proposals [DOI]
  23. 23 Future Directions of Pharmacovigilance Studies Using Electronic Medical Recording and Human Genetic Databases [DOI]
  24. 24 Fundamental concepts and terminology [DOI]
  25. 25 Matching safety to access: global actors and pharmacogovernance in Kenya- a case study [DOI]
  26. 26 Development of antimalaria, antibacterial, anticancer and antitumour drugs from new chemical entities from plant sources [DOI]
  27. 27 Pharmacovigilance in developing countries [DOI]
  28. 28 Active Safety Surveillance in Africa: Pragmatism and Agility [DOI]

Cited by 5

Neuroscience education and research in Cameroon: Current status and future direction

N. E. Mbiydzenyuy, C. A. Pieme, Richard E. Brown · IBRO Neuroscience Reports · 2021

Showing 2 of 5 known citations — external sources report more than can currently be individually listed.

Article metrics

Real usage data collected on this platform.

73

Page views

0

PDF downloads

38

Outbound clicks

5

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.