Pharmacological Activities of a Mongolian Medicinal Plant, Malva mohileviensis Down.
G. Odontuya, G. Enkhmaa, N. Batbayar, R. Naran, K. T. Inngjerdingen, T. E. Michaelsen, B. S. Paulsen
European Journal of Medicinal Plants · pp. 230–241 · Published 6 Jun 2012
10.9734/EJMP/2012/1280Abstract
Aims: To investigate the Mongolian plant M. mohileviensis Down. for the presence of possible bioactive products that could be related to the traditional use of the plant in Mongolia. Methodology: Ethanolic and water extracts of both seeds and herb were tested for anti-inflammatory and DPPH scavenging activity. Polysaccharides were isolated from the seeds using sequence of chromatographic methods. The polysaccharide fraction from the cold water extract was then analyzed for the presence of monosaccharides and their type of linkages by GC and GC-MS. The effect of the polysaccharides on the complement system was then determined. Results: The ethanolic and aqueous extracts of seeds and herbs, as well as crude polysaccharides from cold and hot water extracts exhibited a significant anti-inflammatory activity in the model based on histamine-induced paw edema. Anti-inflammatory effects of all samples were high during the 3rd hour of inflammation. Moreover, the ethanolic extracts of seeds and herbs exhibited DPPH scavenging activity. Phytochemical studies of the cold water seed polysaccharide revealed the presence of an uncommon pectic type polysaccharide. Galacturonic acid (38%) and rhamnose (30%) were present as the main monosaccharides, and linkage analyses revealed that galacturonic acid was present as terminal, 1→4 and 1→3,4 linked units and rhamnose basically as 1→3 linked units. The complement fixation activity was appr. 15 µg/ml, substantially lower than that of the standard used. The results also indicate strongly that the M. mohileviensis and M. verticillata are two different Malva species.
References (24)
- 1 Colorimetric Method for Determination of Sugars and Related Substances [DOI]
- 2 Use of a free radical method to evaluate antioxidant activity [DOI]
- 3 Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs [DOI]
- 4 An Integrated System of Classification of Flowering Plants [DOI]
- 5 An Integrated System of Classification of Flowering Plants. [DOI]
- 6 Changes in Esterification of the Uronic Acid Groups of Cell Wall Polysaccharides during Elongation of Maize Coleoptiles [DOI]
- 7 The Chinese University Of Hong Kong [DOI]
- 8 Preparation, partial characterization and bioactivity of water-soluble polysaccharides from boat-fruited sterculia seeds [DOI]
- 9 Interaction Between Human Complement and a Pectin Type Polysaccharide Fraction, PMII, from the Leaves of Plantago major L. [DOI]
- 10 Extracellular polysaccharides from suspension cultures of Nicotiana plumbaginifolia [DOI]
- 11 Immunomodulating Activity of Plant Polysaccharide Structures [DOI]
- 12 Chemical and biological characterization of pectin-like polysaccharides from the bark of the Malian medicinal tree Cola cordifolia [DOI]
- 13 [19] Gas-liquid chromatographic analysis of constituent carbohydrates in glycoproteins [DOI]
- 14 Heterogeneity and characterisation of mitogenic and anti-complementary pectic polysaccharides from the roots of Glycyrrhiza uralensis Fisch et D.C. [DOI]
- 15 Further characterization of polysaccharides in seeds from Ulmus glabra Huds. [DOI]
- 16 High Molecular Weight Acidic Polysaccharides fromMalva sylvestrisandAlcea rosea [DOI]
- 17 Composition and bioactivity of polysaccharides from tea seeds obtained by water extraction [DOI]
- 18 Plant mucilages. XLII. An anti-complementary mucilage from the Leaves of Malva sylvestris var. mauritiana. [DOI]
- 19 Composition and Antiinflammatory Activity of Polysaccharide Complexes Extracted from Sweet Violet and Low Mallow [DOI]
- 20 Structure and anticomplementary activity of an acidic polysaccharide from the leaves of Malva sylvestris var. mauritiana [DOI]
- 21 Traditional Mongolian Medicine – A Potential for Drug Discovery [DOI]
- 22 Constituents of the seed of Malva verticillata. VI. Characterization and immunological activities of a novel acidic polysaccharide. [DOI]
- 23 Constituents of the Seed of Malva verticillata. VIII. Smith Degradation of MVS-VI, the Major Acidic Polysaccharide, and Anti-complementary Activity of Products. [DOI]
- 24 Constituents of the seed of Malva verticillata. III. Characterization of the major pectic peptidoglycan and oligosaccharides. [DOI]
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