Perforated Peptic Ulcer-Current Management: A Narrative Review
Kumar H. R., Soma M., Saw M. O.
Asian Journal of Medicine and Health · pp. 128–136 · Published 6 Oct 2023
10.9734/ajmah/2023/v21i11927Abstract
Perforated peptic ulcer is a complication of peptic ulcer disease with its incidence being stable despite the introduction of proton pump inhibitors. This condition is seen in older patients with comorbidities and early diagnosis improves the mortality of this condition. The treatment of perforated peptic ulcer is performed by closure of the perforated peptic ulcer, and this procedure can be performed by open or laparoscopic surgery. The current trend over the last few years has been the use of laparoscopic surgery in the management of perforated peptic ulcer and we have conducted this narrative review article to investigate the current trend in management of this condition.
References (60)
- 1 Systematic Review of the Epidemiology of Complicated Peptic Ulcer Disease: Incidence, Recurrence, Risk Factors and Mortality [DOI]
- 2 Perforated peptic ulcer [DOI]
- 3 Perforated and bleeding peptic ulcer: WSES guidelines [DOI]
- 4 Perforated peptic ulcer - an update [DOI]
- 5 Perforated Peptic Ulcer Disease: A Review of History and Treatment [DOI]
- 6 Laparoscopic Repair for Perforated Peptic Ulcer [DOI]
- 7 Epidemiology of perforated peptic ulcer: Age- and gender-adjusted analysis of incidence and mortality [DOI]
- 8 Strategies to improve the outcome of emergency surgery for perforated peptic ulcer [DOI]
- 9 Trends in Perforated Peptic Ulcer: Incidence, Etiology, Treatment, and Prognosis [DOI]
- 10 Randomized Clinical Trial of Laparoscopic Versus Open Repair of the Perforated Peptic Ulcer: The LAMA Trial [DOI]
- 11 Laparoscopic correction of perforated peptic ulcer: first choice? A review of literature [DOI]
- 12 Systematic review comparing laparoscopic and open repair for perforated peptic ulcer [DOI]
- 13 An overview of history, pathogenesis and treatment of perforated peptic ulcer disease with evaluation of prognostic scoring in adults [DOI]
- 14 Scoring systems for outcome prediction in patients with perforated peptic ulcer [DOI]
- 15 What Is the Best Predictor of Mortality in Perforated Peptic Ulcer Disease? A Population-Based, Multivariable Regression Analysis Including Three Clinical Scoring Systems [DOI]
- 16 An Overview of Gastroduodenal Perforation [DOI]
- 17 Changes in the Localization of Perforated Peptic Ulcer and its Relation to Gender and Age of the Patients throughout the Last 45 Years [DOI]
- 18 Epidemiology of perforating peptic ulcer: A population-based retrospective study over 40 years [DOI]
- 19 Management Strategies, Early Results, Benefits, and Risk Factors of Laparoscopic Repair of Perforated Peptic Ulcer [DOI]
- 20 Laparoscopic versus open repair for perforated peptic ulcer: A meta analysis of randomized controlled trials [DOI]
- 21 Significant factors associated with fatal outcome in emergency open surgery for perforated peptic ulcer [DOI]
- 22 Laparoscopic Omental Patch Repair for Perforated Peptic Ulcer [DOI]
- 23 Decreasing incidence of peptic ulcer complications after the introduction of the proton pump inhibitors, a study of the Swedish population from 1974–2002 [DOI]
- 24 Laparoscopic versus open repair of perforated peptic ulcer: Improving outcomes utilizing a standardized technique [DOI]
- 25 Therapeutic management of perforated gastro-duodenal ulcer: Literature review [DOI]
- 26 Surgical management of peptic ulcer disease [DOI]
- 27 Laparoscopy is an available alternative to open surgery in the treatment of perforated peptic ulcers: a retrospective multicenter study [DOI]
- 28 Nonoperative management for perforated peptic ulcer: Who can benefit? [DOI]
- 29 An evaluation of the epidemiology, management and outcomes for perforated peptic ulcers across the North of England over 15 years: A retrospective cohort study [DOI]
- 30 Validation of prognostic scoring systems for predicting 30-day mortality in perforated peptic ulcer disease [DOI]
- 31 Risk factors of perioperative mortality from complicated peptic ulcer disease in Africa: systematic review and meta-analysis [DOI]
- 32 Pattern and outcome of perforated peptic ulcer disease patient in four teaching hospitals in Addis Ababa, Ethiopia: a prospective cohort multicenter study [DOI]
- 33 Surgery for Perforated Peptic Ulcer: Is Laparoscopy a New Paradigm? [DOI]
- 34 Perforated peptic ulcer over 56 years. Time trends in patients and disease characteristics. [DOI]
- 35 Prognostic Factors in Peptic Ulcer Perforations: A Retrospective 14-Year Study [DOI]
- 36 Management of perforated peptic ulcer in a district general hospital [DOI]
- 37 Diagnostic indicators for peptic ulcer perforation at a tertiary care hospital in Thailand [DOI]
- 38 Perforated Peptic Ulcer Disease in a Tertiary Hospital, Addis Ababa, Ethiopia: Five Year Retrospective Study [DOI]
- 39 Non-operative Management of Perforated Peptic Ulcer: A Single Center Experience [DOI]
- 40 Perforated Peptic Ulcer [DOI]
- 41 Evaluation of risk factors for perforated peptic ulcer [DOI]
- 42 Study of Incidence of Peptic Ulcer Perforation in Young Adults: A Hospital Based Study [DOI]
- 43 Changing pattern of perforated PUD: Are NSAIDs to be blamed? [DOI]
- 44 Analysis of risk factors affecting the development of peptic ulcer perforation: case-control study [DOI]
- 45 Is it possible to reduce the surgical mortality and morbidity of peptic ulcer perforations? [DOI]
- 46 Laparoscopic repair for perforated peptic ulcer: our experience, a comparison with the open approach and a review of the literature. [DOI]
- 47 Comparison of features and outcomes of perforated peptic ulcer between Malaysians and foreigners.
- 48 Increasing Number of Comorbidities is Related to Delay to Surgical Management of a Perforated Peptic Ulcer in Patients who Died [DOI]
- 49 The Incidence and Short-term Outcome of Perforated Peptic Ulcers [DOI]
- 50 The use of Laparoscopy In Treatment of Perforated Peptic Ulcer: A Literature Review A Literature Review [DOI]
- 51 A Comparative Study between Peptic Ulcer Perforation Score, Mannheim Peritonitis Index, ASA Score, and Jabalpur Score in Predicting the Mortality in Perforated Peptic Ulcers [DOI]
- 52 Laparoscopic repair of perforated peptic ulcer: a multicenter, propensity score matching analysis [DOI]
- 53 Laparoscopic versus open repair of perforated peptic ulcers: analysis of outcomes and identification of predictive factors of conversion [DOI]
- 54 Primary closure versus Graham patch omentopexy in perforated peptic ulcer: A systematic review and meta-analysis [DOI]
- 55 Are admission laboratory values in isolation meaningful for predicting surgical outcome in patients with perforated peptic ulcers? [DOI]
- 56 Gastric emergencies in older adults: not always the same old story! A tertiary care emergency department observational cohort study [DOI]
- 57 Profiles and Clinical Outcomes of Perforated Peptic Ulcer with Boey Score 3 Treated with External Drainage in Indonesia [DOI]
- 58 Innovative Utilization of Robotic-Assisted Laparoscopy for Repair of Perforated Anterior Duodenal and Posterior Gastric Ulcer at a Hospital With Twenty-Four-Hour da Vinci Xi Capabilities [DOI]
- 59 Combined conservative management and percutaneous peritoneal drainage as damage control approach in high-risk patients with perforated peptic ulcers [DOI]
- 60 International Journal Of Scientific Advances [DOI]
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