Pediatric Septic Shock: Early Recognition and Aggressive Fluid Therapy Improves Outcome
Shahzad Najeeb, Shabana Sarwar, Rafayat Ullah, Asfandyar ., Khurram Saleem, Chetan Das, Tausef Ahmed, Irfan Khan
Journal of Pharmaceutical Research International · pp. 1–6 · Published 18 Dec 2019
10.9734/jpri/2019/v31i630352Abstract
Objective: To establish the effect of aggressive fluid resuscitation in reversing the pediatric septic shock at 1 hour in children younger than 5 years of age presenting in the emergency unit of the hospital. Methods: This was a descriptive, case series study, done for six months, from December 2015 to May 2016, at Pediatric Department of Ayub Medical College Abbottabad. Patients with age range of 1 month to 5 years, presenting in the emergency department with the diagnosis of septic shock having clinical features of tachycardia, tachypnea or hyperthermia along with hypotension and poor capillary refill time were included. All patients received aggressive fluid management. Clinical examination was repeated at the end of one hour for assessment of reversal of shock. Data was collected by self-made Performa. Results: Mean age of study participants was 22.4 ± 17.6 months. Majority of participants 42(57%) were male. Mean weight was 10.3±4.3 kilograms. Mean heart rate was 173.9±17.8 beats per minutes. 67.6% were treated with a third-generation cephalosporin. At the end of one hour of treatment 51 (68.9%) showed the reversal of shock. Conclusion: Majority of childrens who presented with septic shock showed the reversal of shock at one hour of management with weight-based fluid bolus therapy.
References (7)
- 1 International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics* [DOI]
- 2 A Comparison of Albumin and Saline for Fluid Resuscitation in the Intensive Care Unit [DOI]
- 3 Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine* [DOI]
- 4 The Epidemiology of Severe Sepsis in Children in the United States [DOI]
- 5 Early Reversal of Pediatric-Neonatal Septic Shock by Community Physicians Is Associated With Improved Outcome [DOI]
- 6 Role of early fluid resuscitation in pediatric septic shock [DOI]
- 7 Blood glucose control in patients with severe sepsis and septic shock [DOI]
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