Evolutionary Aspects of Cirrhosis in the Hepato-gastroenterology Department of the CHU Gabriel TOURE

Abstract

Introduction: Cirrhosis, a frequent and serious liver disease, is the result of a chronic inflammatory phenomenon leading to an accumulation of fibrosis and a change in the architecture of the liver. The objective of the study was to study the evolutionary aspects of cirrhosis. Methods: The study was longitudinal, analytical descriptive with prospective collection and focused on cirrhotic patients hospitalized in the Hepato-Gastroenterology department of the CHU Gabriel Touré from February 2024 to January 2025. Results: During the study, 185 cases of cirrhosis were collected from 925 hospitalized patients, a frequency of 20%. The average age of cirrhotic patients was 48.35 15 years. The age group [46 years – 60 years] was the most represented. The sex ratio in favor of men was 2.7 and these patients were generally from precarious backgrounds. The diagnosis was often late, with a majority of patients in the decompensation phase. Common clinical signs include ascites (35.7%), abdominal pain (27.56%) and hepatomegaly (3.24%). The complications observed were mainly hepatic encephalopathy (29.73%), hepatocellular carcinoma (21.08%) and digestive hemorrhages (17.84%). The treatment was based on managing complications and antiviral (Tenofovir). Overall mortality was 84.7%. Conclusion: These results highlight the need for early detection, accessible care and better health education of populations at risk.