Pathological Study of Colorectal Cancer in Missan Province

Abstract

Aims: Colorectal cancer (CRC) is a major cause of morbidity and mortality in the worldwide and also ranks as the fifth-leading malignancy and death in Iraq.  This study aimed to provide a present outlook of colorectal diseases among patients with special emphasis on histopathological changes associated CRC in Missan province in Iraq. Methods: This study was covered the period between (First April – 2015 to First October -2015) and all patient`s data were collected from (50) patients aged between (40 -80 or more) with colon and rectal cancer on basis of age, gender and histopathological diagnosis in AL-Sadder hospital in Missan province. Results: Colorectal tumors observed high incidence  with ages between (51-60) years old  represented by  (40%) cases,  while the lowest incidence observed in  ages between (40 -50) years in percentage (12%) cases, CRC were more commonly found in men 28(56%) than women 22(44%) in (P < 0.05). Histopathological examination of the tissue specimens show the commonest type of colorectal cancer was Adeno carcinoma in the colon 22(44%) cases, Ulcerative colitis in the colon were represented by 10(20%) cases, Mucinoid adenocacinoma were found in 8(16%) cases, P eutz –jeghers syndrome were found in 3(6%) cases, and Lymphoma in the colon (Lymphoplasmocyte) observed in 7(14 %) cases. In conclusion the incidence of CRC was common in age older than fifty years in this study, commonest type of CRC was adenocarcinoma in colon, and the ulcerative colitis in chronic stage may lead to hyperplastic to the epithelial cells in colon. Conclusion: Proper implementation of preventive measures such as changing lifestyle factors might enhance control of colorectal disease.