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Research Article Open access CC BY 4.0

Overview on Ocular Manifestations of Albinism- A Review

Abdulrahman M. Albahlool, Fatema Adel Almajed, Maryam Essa Alwabari, Rana Mohammed Hilmi, Reem Mohammed Saad Abahussain, Sarah Mohammed Alasgah, Rima Salman M. Bnfadliah, Khalid Alwalid Alekrish, Zinab M. Abuammah Alharbi, Mohammad Maitham Almomen

Journal of Pharmaceutical Research International · pp. 300–308 · Published 7 Aug 2021

10.9734/jpri/2021/v33i40A32248

Abstract

Albinism is a set of heritable disorders in ectoderm-derived tissue linked with reduced or missing melanin. Reduce melanin synthesis might include the skin, hair follicles and the eye, causing eyelid or locating the eye in the main, leading to eye albinism. Common eye symptoms include foveal hypoplasia, fundal hypopigmentation, iris transillumination, nystagma, visual acuity reduction, stereopsis decreased or absent, squint, and abnormalities in refractive functionality. Fixing the refractive defect, sun glasses or specific photo aversion filter lenses and prismatism for an irregular head posture may be needed. Operation with strabismus is typically unneeded but may be done to enhance the peripheral fields of visual fusion. In this review, we summarize ocular manifestations of albinism.

Albinism ocular albinism symptoms manifestations ophthalmology

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