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Research Article Open access CC BY 4.0

Cardiac Sarcoidosis Leading to Restrictive Cardiomyopathy: A Case Report of Fatal Ventricular Fibrillation in a 45-Year-Old Male

S. EJJEBLI, A. ALTIMIMI, I. Rezzouk, A. ELMAHI, G. Benouna, R. HABBAL

Asian Journal of Cardiology Research · pp. 331–336 · Published 31 May 2025

10.9734/ajcr/2025/v8i1282

Abstract

Cardiac sarcoidosis is a rare but serious manifestation of systemic sarcoidosis, affecting the heart muscle and leading to significant morbidity and mortality. We report the case of a 45-year-old male with a decade-long history of systemic sarcoidosis, who was admitted with symptoms of global heart failure. Diagnostic evaluation included cardiac magnetic resonance imaging (MRI) and Holter monitoring, which revealed myocardial inflammation and arrhythmias. Despite medical management, his condition deteriorated, culminating in fatal ventricular fibrillation. This case underscores the challenges in diagnosing and managing cardiac sarcoidosis, the progression to restrictive cardiomyopathy, and the critical importance of early detection and risk stratification to prevent fatal arrhythmias.

Sarcoidosis restrictive cardiomyopathy Heart failure

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