One-Year Clinical Evaluation of Four Desensitizing Agents in the Management of Cervical Dentin Hypersensitivity: A Randomized, Prospective, Blinded Clinical Trial

Abstract

Objective: The objective of this randomized, prospective, and blinded clinical study was to evaluate the efficacy of four desensitizing agents in the long-term treatment of cervical dentin hypersensitivity (HD) and their impact on the quality of life of the research volunteers. Materials and Methods: A total of 116 teeth were randomized and divided into 4 groups (n=29 teeth) according to the applied treatment: GD - Gluma Desensitizer; CV - Clinpro White Varnish; SB - Single Bond; AS - AdheSE. Sensitivity levels were assessed using the Visual Analog Scale (VAS) immediately after the application of each material, and at 7, 30, 60, and 360 days post-treatment. The patients completed a quality of life questionnaire. Data were analyzed using Kruskall Wallis test with the Dwass-Steel-Critchlow-Fligner post-test were used for intergroup evaluation (p<0.05). Results: In the intragroup comparison, there was a statistically significant decrease (p<0.05) in sensitivity from the initial period for the GD, CV, and AS groups. There was an improvement in the patients' quality of life. Conclusion: This clinical study demonstrated the effectiveness of the desensitizing agents in the long-term treatment of cervical dentin hypersensitivity, with the exception of SB. Clinical relevance: HD is a clinical condition that directly affects patients' quality of life. This study revealed three effective desensitizing agents for a prolonged period.