Phytochemistry and Pharmacological Evidence of East Asian Crowberry Reported as Empetrum nigrum var. japonicum or E. nigrum subsp. asiaticum: A Critical Review of Potential Chemotypic Differentiation

References (57)

1. 1 Bezverkhniaia, 2023, Phytochemistry, Ethnopharmacology and Pharmacology of the Genus Empetrum: A Review [DOI]
2. 2 Jurikova, T., Mlcek, J., Skrovankova, S., Balla, S., Sochor, J., Baron, M., and Sumczynski, D. (2016). Black Crowberry (Empetrum nigrum L.) Flavonoids and Their Health Promoting Activity. Molecules, 21. [DOI]
3. 3 Lorion, 2021, Crowberry (Empetrum): A Chief Arctic Traditional Indigenous Fruit in Need of Economic and Ecological Management [DOI]
4. 4 Plants of the World Online (2026, August 28). Empetrum nigrum L. Facilitated by the Royal Botanic Gardens, Kew. Available online: https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:30371508-2.
5. 5 Lavola, 2017, Phytochemical Variation in the Plant-Part Specific Phenols of Wild Crowberry (Empetrum hermaphroditum Hagerup) Populations [DOI]
6. 6 Bai, 2020, Two New Compounds from Empetrum nigrum var. japonicum [DOI]
7. 7 Bao, 2020, Structure Elucidation and NMR Assignments of a New Dihydrochalcone from Empetrum nigrum subsp. asiaticum (Nakai ex H. Ito) Kuvaev [DOI]
8. 8 Sun, 2025, A New Dihydrochalcone Glycoside from Empetrum nigrum var. japonicum [DOI]
9. 9 Oka, 2020, Isolation, Synthesis, and Biological Activities of a Bibenzyl from Empetrum nigrum var. japonicum [DOI]
10. 10 Bao, 2022, Nigrumol A, a New Triterpenoid from Empetrum nigrum subsp. asiaticum (Nakai ex H. Ito) Kuvaev [DOI]
11. 11 Zhang, 2014, Chemical Constituents of Empetrum nigrum var. japonicum
12. 12 Wang, 2016, Chemical Constituents of Ethyl Acetate Extract of Empetrum nigrum var. japonicum and Their Effect on Alcoholic Fatty Liver of Rats
13. 13 Zhao, 2016, Chalcones from Empetrum nigrum var. japonicum
14. 14 Ogawa, 2008, Anthocyanin Composition and Antioxidant Activity of the Crowberry (Empetrum nigrum) and Other Berries [DOI]
15. 15 Koskela, 2010, Variation in the Anthocyanin Concentration of Wild Populations of Crowberries (Empetrum nigrum L. subsp. hermaphroditum) [DOI]
16. 16 Bae, 2015, Anthocyanin Profile and Antioxidant Activity of Various Berries Cultivated in Korea
17. 17 Heinonen, 1999, Screening of Selected Flavonoids and Phenolic Acids in 19 Berries [DOI]
18. 18 Mattila, 2004, Distribution and Contents of Phenolic Compounds in Eighteen Scandinavian Berry Species [DOI]
19. 19 Laaksonen, 2011, Orosensory Contributing Compounds in Crowberry (Empetrum nigrum) Press-Byproducts [DOI]
20. 20 Ponkratova, 2022, A New Dimethoxy Dihydrochalcone Isolated from the Shoots of Empetrum nigrum L [DOI]
21. 21 Martz, 2013, Phenolic Responses of Mountain Crowberry (Empetrum nigrum ssp. hermaphroditum) to Global Climate Change are Compound Specific and Depend on Grazing by Reindeer (Rangifer tarandus) [DOI]
22. 22 Ponkratova, 2021, A New Bibenzyl and 9,10-Dihydrophenanthrene Derivative from Aerial Parts of Crowberry (Empetrum nigrum L.) [DOI]
23. 23 Li, 2015, Dibenz[b,f]oxepin and Antimycobacterial Chalcone Constituents of Empetrum nigrum [DOI]
24. 24 Toiron, 1995, A New Skeletal Triterpenoid Isolated from Empetrum nigrum [DOI]
25. 25 Juríková, T., Mlček, J., Balla, Š., Ondrášová, M., Dokoupil, L., Sochor, J., Ďurišová, L.U., Eliáš, P., Adámková, A., and Baroň, M. (2021). The Elucidation of Total Polyphenols, Individual Phenolic Compounds, Antioxidant Activity of Three Underutilized Fruit Species—Black Crowberry, Honeyberry, and European Cranberry with Their Accumulation. Agronomy, 11. [DOI]
26. 26 Johansson, 1997, Geographical Variations in Seed Oils from Rubus chamaemorus and Empetrum nigrum [DOI]
27. 27 Hosoya, 2026, 1H-NMR-Based Anthocyanin Profiles and Antioxidant Capacities of Swedish Crowberry (Empetrum nigrum L.): Effects of Harvest Time and Location [DOI]
28. 28 Zhang, 2021, Optimization of Phenolics and Flavonoids Extraction from the Fruit of Empetrum nigrum var. japonicum from Jeju Island in South Korea [DOI]
29. 29 Pilon, 2015, Comprehensive Analysis of Phenolic Compounds and Abscisic Acid Profiles of Twelve Native Canadian Berries [DOI]
30. 30 Kellogg, 2010, Alaskan Wild Berry Resources and Human Health under the Cloud of Climate Change [DOI]
31. 31 Oprica, 2016, Antioxidants Content in Empetrum nigrum Fresh and Dried Fruits
32. 32 Park, 2012, Antioxidative Effects of Two Native Berry Species, Empetrum nigrum var. japonicum K. Koch and Rubus buergeri Miq., from the Jeju Island of Korea [DOI]
33. 33 Whaley, 2023, Analysis of Empetrum nigrum L. Lipophilic Secondary Metabolites, their Metabolomic Profiles and Antioxidant Activity [DOI]
34. 34 Theoduloz, 2024, Phenolics and Enzyme Inhibitors from the Patagonian Empetrum rubrum Berries [DOI]
35. 35 Schneider, C., Gonzalez-Reyes, M., Vergara, C., Fuica-Carrasco, C., and Zapata, P. (2024). Antioxidant and Antifungal Activities and Characterization of Phenolic Compounds Using High-Performance Liquid Chromatography and Mass Spectrometry (HPLC-MS) in Empetrum rubrum Vahl ex Willd. Plants, 13. [DOI]
36. 36 Zhao, W., Huang, L., Xu, S., Wu, J., Wang, F., Li, P., Li, L., Tian, M., Feng, X., and Chen, Y. (2024). Identification of One O-Methyltransferase Gene Involved in Methylated Flavonoid Biosynthesis Related to the UV-B Irradiation Response in Euphorbia lathyris. Int. J. Mol. Sci., 25. [DOI]
37. 37 Madani, H., Escrich, A., Hosseini, B., Sanchez-Muñoz, R., Khojasteh, A., and Palazon, J. (2021). Effect of Polyploidy Induction on Natural Metabolite Production in Medicinal Plants. Biomolecules, 11. [DOI]
38. 38 Zahedi, 2014, Overproduction of Valuable Methoxylated Flavones in Induced Tetraploid Plants of Dracocephalum kotschyi Boiss [DOI]
39. 39 Linko, 1983, Anthocyanin Contents of Crowberry and Crowberry Juice
40. 40 Wollenweber, 1993, Bibenzyls from Crowberry Leaves [DOI]
41. 41 Tsvetov, 2022, Ultrasound-Assisted Extraction of Phytochemicals from Empetrum hermaphroditum Hagerup Using an Acid-Based Deep Eutectic Solvent: Kinetics and Optimization [DOI]
42. 42 Gao, 2022, A Green Ultrasound-Assisted Enzymatic Extraction Method for Efficient Extraction of Total Polyphenols from Empetrum nigrum and Determination of its Bioactivities [DOI]
43. 43 Kim, 2009, Risk Reduction of Ethyl Acetate Fraction of Empetrum nigrum var. japonicum via Antioxidant Properties Against Hydrogen Peroxide-Induced Cell Damage [DOI]
44. 44 Kim, 2011, Empetrum nigrum var. japonicum Extract Suppresses γ-Ray Radiation-Induced Cell Damage via Inhibition of Oxidative Stress [DOI]
45. 45 Kim, 2013, Empetrum nigrum var. japonicum Extract Suppresses Ultraviolet B-Induced Cell Damage via Absorption of Radiation and Inhibition of Oxidative Stress
46. 46 Hyun, 2016, Antioxidant, α-Glucosidase Inhibitory and Anti-Inflammatory Effects of aerial parts extract from Korean crowberry (Empetrum nigrum var. japonicum) [DOI]
47. 47 Bae, 2016, In Vitro and In Vivo Antiangiogenic Activity of Crowberry (Empetrum nigrum var. japonicum)
48. 48 Yang, 2012, Activity of the Ethanolic Extract from Fruit of Empetrum nigrum var. japonicum on CCl4-Induced Liver Injury in BALB/c Mice [DOI]
49. 49 Wang, 2022, Crowberry Inhibits Cell Proliferation and Migration through a Molecular Mechanism That Includes Inhibition of DEK and Akt Signaling in Cholangiocarcinoma [DOI]
50. 50 Paudel, 2014, Estimation of Antioxidant, Antimicrobial Activity and Brine Shrimp Toxicity of Plants collected from Oymyakon region of the Republic of Sakha (Yakutia), Russia [DOI]
51. 51 Park, 2013, Effectiveness of Crowberry on Plasma Total Antioxidant Status, Lipid Profile and Homocysteine
52. 52 Bezverkhniaia, 2020, Screening Study for Anticonvulsive Activity of Lipophilic Fractions from Empetrum nigrum L [DOI]
53. 53 Smiljanic, S., Messaraa, C., Lafon-Kolb, V., Hrapovic, N., Amini, N., Osterlund, C., and Visdal-Johnsen, L. (2022). Betula alba Bark Extract and Empetrum nigrum Fruit Juice, a Natural Alternative to Niacinamide for Skin Barrier Benefits. Int. J. Mol. Sci., 23. [DOI]
54. 54 Jasim, H.A., Nahar, L., Jasim, M.A., Moore, S.A., Ritchie, K.J., and Sarker, S.D. (2021). Chalcones: Synthetic Chemistry Follows Where Nature Leads. Biomolecules, 11. [DOI]
55. 55 Yu, 2024, Edible-plant derived 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone exert dual effects on invigorating triple-negative breast cancer apoptosis [DOI]
56. 56 Lee, J.-H., Lee, E.-S., Lee, J.-S., and Seo, C.-W. (2025). Mapping Endangered Plant Distributions, Species Richness, and Climate Refugia Under SSP Climate Scenarios in South Korea. Plants, 14. [DOI]
57. 57 Nechiporenko, I., Akimova, S., and Semenova, N. (2025). Mycorrhization of Black Crowberry (Empetrum nigrum L.) After In Vitro Propagation with Mineral Fertilizers. Horticulturae, 11. [DOI]

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