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Research Article Open access CC BY 4.0

Multiple Drug Resistance in Burn Patients

Abeer Mansour Abdel Rasool, Ahmed Shoaib Karmoosh

Journal of Advances in Medical and Pharmaceutical Sciences · pp. 21–34 · Published 19 Jul 2024

10.9734/jamps/2024/v26i7699

Abstract

Infections, the most frequent outcomes and the leading cause of death in burn patients, reproduce in milieux generated by burn lesions, Severely burned patient’s immunity is weakened, thus systemic infections such as pneumonia and urinary tract infections are likely to develop. New diseases which have come up and are hardly combatted by many drugs offer a major threat in therapy; new antimicrobial medicines and effective measures that prevent infection have to be used. Due to their high mortality, these infections form a major concern to the increasing cases of MDROs in burn victims. Given that the surfaces of burn related injuries are broad, the patients’ immune systems are compromised, while they require several surgeries and lengthy hospitalization, they are easy targets for MDROs. Among the published studies, it is revealed that multidrug-resistant organisms (MDROs) are on the rise among burn patients, which poses a threat to patient outcomes as well as the treatment of the condition. As a result of skin degeneration, long-term hospitalizations, and the necessity for invasive procedures, all of which contribute to the development of infections, burn patients are particularly vulnerable.

Infections burn multiple drug resistance

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