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Research Article Open access CC BY 4.0

Synthesis, Characterization and Biological Activity of a Bidentate NS Schiff Base Containing S-Benzyl Dithiocarbazate and Its Zr(IV), Sn(II) Complexes

Md. Kudrat-E- Zahan, Md. Faruk Hossen, Rausan Zamir, Md. Ali Asraf

Asian Journal of Research in Biochemistry · pp. 14–24 · Published 10 Aug 2020

10.9734/ajrb/2020/v7i230134

Abstract

Zr (IV) and Sn (II) complexes were prepared with bidentate ligand, benzyl 2-(3-phenylallylidene) hydrazinecarbodithioate, derived from the condensation of S-benzyldithiocarbazate (SBDTC) with cinnamaldehyde and characterized by microanalysis, molar conductance and magnetic measurements, IR, electronic and ESI-MS studies. It was found that the ligand coordinated to the metal center through azomethine nitrogen and thiol sulfur atoms to form octahedral complexes with both the metal ions. The antimicrobial activities of the ligand and its complexes were investigated against the gram-positive and gram-negative bacteria and the fungus strain. The metal complexes showed strong activity than the free ligand.

Schiff base metal complex antibacterial activity antifungal activity.

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