Niosomes: A Promising Drug Delivery System in Transdermal Drug Delivery (TDDS)
Vibhavari M. Chatur, Shashikant N. Dhole
Journal of Pharmaceutical Research International · pp. 6–17 · Published 8 Nov 2021
10.9734/jpri/2021/v33i48B33254Abstract
Infectious disease treatment and immunisation have undergone a transformative change in recent years. With the advancement of biotechnology and genetic engineering, a large number of disease-specific biological have been created, as well as a focus on delivering these biological effectively. Niosomes are vesicular Nano carriers that are gaining popularity as a potential transdermal drug delivery system due to properties like enhanced drug penetration, a local depot for sustained drug release, and a rate-limiting membrane for modulating systemic absorption of drugs through the skin. Niosomes are non-ionic surfactant-based vesicles that are biodegradable, relatively nontoxic, more stable, and less expensive than liposomes. This analysis gives a high-level overview of niosomes, including their chemical composition, structure, benefits, and applications, as well as some general observations on niosomes as percutaneous permeation enhancers.
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