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Research Article Open access CC BY 4.0

Nigella sativa Derived Phytochemicals against Cough

Diptiprajnya Sahoo, Minati Nayak, Sidhartha Ray, Mukundjee Pandey, Kalpita Bhatta, Sushree Susmita Palei, Debasmita Rautaray

Journal of Pharmaceutical Research International · pp. 98–101 · Published 20 Jun 2020

10.9734/jpri/2020/v32i930535

Abstract

Nigella sativa plant extract is traditionally used to cure cough. It is caused by Bordetella pertussis. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that p-cymene can effectively deactivate the adenylate cyclase thereby interrupting the life cycle of the organism.

Phytochemicals Nigella sativa Bordetella pertussis cough.

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