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Research Article Open access CC BY 4.0

Newer Treatment Modalities in Urticaria

Meghana Pendam, Bhushan Madke

Journal of Pharmaceutical Research International · pp. 472–476 · Published 16 Dec 2021

10.9734/jpri/2021/v33i59A34294

Abstract

Wheals (hives), angioedema, or both are symptoms of urticaria, a chronic clinical disorder. Urticaria has a complicated pathogenesis, as well as a large disease burden, a negative effect on health-care expenditures and quality of living. Urticaria could also be a chronic condition that affects up to 1% of the general population at some stage in their lives and can drastically impair quality life. The use of second-generation, non-sedating antihistamines has replaced antihistamines to use as the first-line therapy. However, urticaria can be difficult to manage in some cases; in these cases, alternate treatment approaches must be considered. This article reviews antihistamines, leukotriene antagonists, anti-inflammatory drugs, biologicals, subcutaneous autologous serum therapy, doxepin, cyclosporine ,tranexamic acid and other newer treatment modalities.

Urticaria wheals histamine

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