Neuropsychology and Genetics of Psychotropic Drug Users - Lithuanian COMT Gene Polymorphisms Frequencies
Daniele Ramonaite, Liudas Vincentas Sinkevicius, Danielius Serapinas
Journal of Advances in Medicine and Medical Research · pp. 164–170 · Published 13 Aug 2022
10.9734/jammr/2022/v34i2131534Abstract
Background: Addiction is increasing worldwide, so there is a need to study the neuropsychology and genetics of the emergence of this process. In our study, we have focused on the characteristics of the COMT gene in psychotropic drug users. Aim of the Study: Investigation of the frequency of COMT gene polymorphisms in psychotropic drug users in Lithuania as well to review literature of addiction neuropsychology and genetics. Materials and Methods: The study involved 73 patients aged 18 to 75 years.from InMedica Santariškės clinics who were tested for A (adenine), G (guanine) alleles and A/A, A/G and G/G COMT genotypes. Results: The study analyzed the frequency of comt gene polymorphisms in in 73 psychotropic drug users. It was identified A/A genotypes in 17, A/G in 37, G/G in 19 participants. Conclusion: In studied cohort we detected high rates of more rare A/A genotype , which is related to lower amount of COMT enzyme and in result higher catecholamines level.
Cited by 0
No indexed citations yet.
Related research
- Current Status of Glossina Population Ecology — shares topic coverage
- Applied Genetics and Plant Breeding in 21st Century for Crop Improvement – Status and Prospects — shares topic coverage
- Efficient Synthesis of Novel 10R-Pyrido[4,3-a]Phenazines, Including the Series Progenitor — shares topic coverage
- Study of Factor VIII Inhibitor and F8 Gene Mutations in Persons with Hemophilia A from Benin — shares topic coverage
- Salient Genetic Notes on Small-RNAs and their Applications in Agricultural Biotechnology — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.