Neurological Complications of  COVID-19 Vaccination: A Case Report of Generalized Convulsive Status Epilepticus

Machlusil Husna; Ria Damayanti; Priyo Atdisuramad

doi:10.9734/ijmpcr/2023/v16i4355

Research Article Open access CC BY 4.0

Neurological Complications of COVID-19 Vaccination: A Case Report of Generalized Convulsive Status Epilepticus

Machlusil Husna, Ria Damayanti, Priyo Atdisuramad

International Journal of Medical and Pharmaceutical Case Reports · pp. 80–86 · Published 7 Dec 2023

10.9734/ijmpcr/2023/v16i4355

Abstract

Generalized convulsive status epilepticus (GCSE) is a life-threatening condition characterized by prolonged seizure activity that affects both sides of the brain. Despite its high mortality rate, GCSE is a relatively rare complication of COVID-19 vaccination. In this case report, we presented a 28-year-old male with no known history of neuropsychiatric disorders who developed GCSE following the first dose of the mRNA COVID-19 vaccine. It is plausible that the COVID-19 vaccine played a role in the development of GCSE in this patient. This case report also provides brief review potential association between COVID-19 vaccination and GCSE. Enhanced post-vaccination monitoring protocols are essential for ensuring the safety of COVID-19 vaccination for patients with underlying medical conditions or those at heightened risk of neurological complications.

Generalized Convulsive Status Epilepticus (GCSE) mRNA COVID-19 vaccine COVID-19 vaccination

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Machlusil Husna, Ria Damayanti, Priyo Atdisuramad (2023). Neurological Complications of COVID-19 Vaccination: A Case Report of Generalized Convulsive Status Epilepticus. International Journal of Medical and Pharmaceutical Case Reports , 80–86. https://doi.org/10.9734/ijmpcr/2023/v16i4355

Affiliations

Machlusil Husna — Division of Epilepsy, Department of Neurology, Faculty of Medicine, Universitas Brawijaya, Dr. Saiful Anwar General Hospital, Malang, Indonesia.
Ria Damayanti — Division of Epilepsy, Department of Neurology, Faculty of Medicine, Universitas Brawijaya, Dr. Saiful Anwar General Hospital, Malang, Indonesia.
Priyo Atdisuramad — Department of Neurology, Faculty of Medicine, Universitas Brawijaya, Dr. Saiful Anwar General Hospital, Malang, Indonesia.

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