Nerve Conduction Study in Healthy Elderly Subjects in Central India

Abstract

Background: Electrodiagnostic study is performed in a neurophysiology lab diagnosed peripheral neuropathy. Effect of ageing on nerve and muscle inform of muscle contractility decreased, change in the metabolism of muscle and neuromuscular junction transmission and reduced nerve conduction velocity. As the ageing population increases, information regarding the course of normal ageing, its impact on the nervous system, ways to maintain wellness, and disease that impact the elderly and their management is necessary. Therefore, this proposed study aims to elucidate the effect of physiological factors (height, Body Mass Index and gender) on nerve conduction study and find out the normative data for healthy elderly subjects in central India. Objectives: 1) To establish normative data of nerve conduction study in Ulnar, median Tibial, and Peroneal nerves in normal healthy elderly subjects. 2) To find out the effect of height, body mass index and gender on nerve conduction in healthy elderly subjects. Methodology:   This will be a Cross-sectional study with participants aged > 60 years of both healthy subjects will be included in the study. The procedure will be performed after written consent from all the subjects. A normative data consist of parameters as distal motor Latency, peak to peak Amplitude and conduction velocity in motor nerve; peak to peak amplitude and nerve conduction velocity for sensory nerves. F wave minimum latency of motor nerve Nerve conduction study will be performed on Neuron Spectrum 5 (Neurosoft) machine.    Results: Normative data will compare with globally published literature. Conclusion: The study is expected to draw observation in relation to variables cited with the objectives, which will be compared to draw inference over normative data of nerve conduction studies in healthy elderly subjects from the Wardha district.