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Research Article Open access CC BY 4.0

Studies of Pharmaceutical Active Ingredients in Drugs through Radiological Parameters

A. Manjunath, B. R. Kerur

Physical Science International Journal · pp. 186–191 · Published 19 Jun 2015

10.9734/PSIJ/2015/18029

Abstract

Mass attenuation coefficient and effective atomic number of the active pharmaceutical ingredients viz, Alprazolam, Amiodar, Amiodarone, Ciprofloxacin, Diclofenac Sodium, Femotidine and Nimesulide have been calculated over a wide energy range from 1 keV to 100 GeV for total and partial photon interactions by using WinXCom. The obtained data shows that the change in mass attenuation coefficient and electron density varies with energy and chemical composition of the active pharmaceutical ingredients (API’s) in drugs. The results in the variation of photon interaction with energy and effective atomic number of the API’s in drug are shown in the logarithmic graphs.  

API pharmaceutical WiXCom absorption edge

Cited by 3

DETERMINATION OF RADIOLOGICAL PARAMETERS OF SOME ACTIVE PHARMACEUTICAL INGREDIENTS USING WINXCOM SOFTWARE IN THE ENERGY RANGE 1KEV TO 100KEV

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Radiological Properties of Some Chemotherapy Drugs for Electron, Proton and Carbon Ion Interactions in the Energy Region 10 keV – 400 MeV

Mehmet Büyükyıldız, Murat Türemiş · Celal Bayar Üniversitesi Fen Bilimleri Dergisi · 2023

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