Demographic Implications of Serum Prostate-specific Antigen Level Distribution among Men in Tudun Wada Jos and Its Environs

Abstract

Background: Prostate-specific antigen (PSA) is an antigen produced primarily by the ductal and acinar cells of the prostatic epithelium, as well as male periurethral glands, and usually secreted into the seminal fluid. Its primary function is the liquefaction of the seminal coagulum in the human ejaculate. An increase in the PSA level is a health concern and requires medical intervention. Therefore, understanding the factors that affect the PSA is important. Aim: The study was aimed at determining the impact of demographic parameters on serum PSA level among men in the Church of Christ in Nations (COCIN) LCC Tudun Wada Jos and its environment. Methodology: The cross-sectional study was conducted among 50 elderly men at the Church of Christ in Nations (COCIN) LCC Tudan wada, Jos City of Plateau State. Based on set criteria, subjects were selected using a simple random sampling technique. A blood sample (5ml) was collected via venipuncture and the serum of the collected sample was assayed for the PSA using the chemiluminescence immunoassay method. Results: Results reveal that there was a significant increase in the PSA level among the subjects with increasing age group, p-value<0.05. Other demographic parameters had no significant impact on the PSA level, p-value>0.05. Conclusion: This study has shown that an increase in age has a corresponding rising impact on the PSA level among elderly men living in Tudan wada, Jos.