Native Vietnamese Medicinal Plants with Anti-atopic Dermatitis Activity: A Systematic Review
Do Hoang Thu Trang, Hoang Le Son
Journal of Complementary and Alternative Medical Research · pp. 1–24 · Published 13 Dec 2016
10.9734/JOCAMR/2016/30578Abstract
Aims: Medicinal plants have always been highly valued as an accessible traditional treatment for atopic dermatitis in Vietnam. Accordingly, this review aims to assemble and discuss plants with validated anti-atopic dermatitis potency in the country, putting a great emphasis on the practice of phytomedicines and the development of plant-based products for dermatologic conditions. Existing concerns and future perspectives are included to ensure comprehensiveness of the overview. Methodology: This review is a systematic compilation of published in vitro studies, clinical trials and case studies on the effectiveness of single plant extracts in alleviating atopic dermatitis that can be found in Vietnam. Results: 39 publications presenting 31 plant species were collected in total. Preparation of plant extracts and route of administration varied slightly between the studies. Root and leaves are plant parts that were most commonly investigated (25.00% and 22.50%). Disease symptoms were mostly induced on NC/Nga mice (61.54%) using sensitizers like 2,4-dinitrochlorobenzene (28.57%), 1-fluoro-2,4-dinitrobenzene (25.71%) and Dermatophagoides farinae body extract (28.57%). Effects of plant extracts on epidermal/dermal thickness, IgE serum level, infiltration of immune cells and hyperproduction of inflammatory cytokines were intensively investigated in the collected studies. Conclusion: This review highlights the enormous potential of medicinal plants as an effective and easily accessible alternative therapy against atopic dermatitis. The use of these still needs to be further supported by scientific evidence and controlled by strict regulations to ensure good practice and stable development of phytomedicines.
References (64)
- 1 Solid State Fermentation [DOI]
- 2 Bioactive phenolic compounds: Production and extraction by solid-state fermentation. A review [DOI]
- 3 Immune mechanisms leading to atopic dermatitis [DOI]
- 4 Persimmon leaf extract and astragalin inhibit development of dermatitis and IgE elevation in NC/Nga mice [DOI]
- 5 Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-κB activation and adhesion molecule expression [DOI]
- 6 An over the counter moisturizer is as clinically effective as, and more cost-effective than, prescription barrier creams in the treatment of children with mild to moderate atopic dermatitis: A randomized, controlled trial [DOI]
- 7 Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid [DOI]
- 8 In Vitro and In Vivo Antiallergic Effects of Glycyrrhiza glabra and Its Components [DOI]
- 9 Topical treatment of atopic dermatitis with St. John's wort cream – a randomized, placebo controlled, double blind half-side comparison [DOI]
- 10 Oral Intake of Glucosylceramide Improves Relatively Higher Level of Transepidermal Water Loss in Mice and Healthy Human Subjects [DOI]
- 11 Illicium verum extract inhibits TNF-α- and IFN-γ-induced expression of chemokines and cytokines in human keratinocytes [DOI]
- 12 Platycodon grandiflorum root-derived saponins attenuate atopic dermatitis-like skin lesions via suppression of NF-κB and STAT1 and activation of Nrf2/ARE-mediated heme oxygenase-1 [DOI]
- 13 Inhibitory effects of Cinnamomum cassia extract on atopic dermatitis-like skin lesions induced by mite antigen in NC/Nga mice [DOI]
- 14 Effect of Sophora flavescens Aiton extract on degranulation of mast cells and contact dermatitis induced by dinitrofluorobenzene in mice [DOI]
- 15 Effects of Scutellariae radix and Aloe vera gel extracts on immunoglobulin E and cytokine levels in atopic dermatitis NC/Nga mice [DOI]
- 16 Topical application of Rehmannia glutinosa extract inhibits mite allergen-induced atopic dermatitis in NC/Nga mice [DOI]
- 17 Anti-inflammatory activities of Dictamnus dasycarpus Turcz., root bark on allergic contact dermatitis induced by dinitrofluorobenzene in mice [DOI]
- 18 Allergic contact dermatitis to Aloe vera [DOI]
- 19 Topical application of Kochia scoparia inhibits the development of contact dermatitis in mice [DOI]
- 20 Effects of aDictamnus dasycarpusT. Extract on Allergic Models in Mice [DOI]
- 21 Inhibitory effect of Platycodon grandiflorum on TH1 and TH2 immune responses in a murine model of 2,4-dinitrofluorobenzene–induced atopic dermatitis–like skin lesions [DOI]
- 22 Alleviation of atopic dermatitis-related symptoms by Perilla frutescens Britton [DOI]
- 23 Effects of Dictamnus dasycarpus Turcz., root bark on ICAM-1 expression and chemokine productions in vivo and vitro study [DOI]
- 24 Current management of atopic dermatitis and interruption of the atopic march [DOI]
- 25 Atopic dermatitis: Review of immunopathogenesis and advances in immunosuppressive therapy [DOI]
- 26 Inhibition of Tumor Necrosis Factor-αProduction by Orally Administering a Perilla Leaf Extract [DOI]
- 27 A double-blind, placebo-controlled trial of anAloe vera (A. barbadensis)emulsion in the treatment of seborrheic dermatitis [DOI]
- 28 Inhibitory Effects of Heartwood Extracts of Broussonetia kazinoki Sieb on the Development of Atopic Dermatitis in NC/Nga Mice [DOI]
- 29 Oral administration of Uncariae rhynchophylla inhibits the development of DNFB-induced atopic dermatitis-like skin lesions via IFN-γ down-regulation in NC/Nga mice [DOI]
- 30 Skin Reaction Induced by Aldehydes for Food Flavoring Agents. [DOI]
- 31 Topical application of an ethanol extract prepared from Illicium verum suppresses atopic dermatitis in NC/Nga mice [DOI]
- 32 Platycodon grandiflorus alleviates DNCB-induced atopy-like dermatitis in NC/Nga mice [DOI]
- 33 Morus alba L. suppresses the development of atopic dermatitis induced by the house dust mite in NC/Nga mice [DOI]
- 34 Improvement of Atopic Dermatitis-Like Skin Lesions by Platycodon grandiflorum Fermented by Lactobacillus plantarum in NC/Nga Mice [DOI]
- 35 Treatment of mild to moderate seborrhoeic dermatitis with MAS064D (Sebclair®), a novel topical medical device: results of a pilot, randomized, double‐blind, controlled trial [DOI]
- 36 An outbreak of contact dermatitis from Rhus verniciflua (Toxicodendron vernicifluum) [DOI]
- 37 Allergic contact dermatitis from cinnamon as an odour‐neutralizing agent in shoe insoles [DOI]
- 38 Atopic dermatitis management: comparing the treatment patterns of dermatologists in Japan, U.S.A. and U.K. [DOI]
- 39 Patient‐reported outcomes from a multicenter, randomized, vehicle‐controlled clinical study of MAS063DP (Atopiclair™) in the management of mild‐to‐moderate atopic dermatitis in adults [DOI]
- 40 Macelignan Inhibits Histamine Release and Inflammatory Mediator Production in Activated Rat Basophilic Leukemia Mast Cells [DOI]
- 41 Effects of Schisandra chinensis Turcz. fruit on contact dermatitis induced by dinitrofluorobenzene in mice [DOI]
- 42 Immunomodulatory Effect of Eriobotrya japonica Seed Extract on Allergic Dermatitis Rats [DOI]
- 43 Effect of orally administered Eriobotrya japonica seed extract on allergic contact dermatitis in rats [DOI]
- 44 Cinnamomum cassia bark produced by solid-state fermentation with Phellinus baumii has the potential to alleviate atopic dermatitis-related symptoms [DOI]
- 45 Occupational allergic contact dermatitis from Perilla frutescens (shiso) [DOI]
- 46 Dwarfism Following Long-term Topical Corticosteroid Therapy [DOI]
- 47 Contact sensitivity to toothpaste. [DOI]
- 48 Perioral dermatitis from marjoram, bay leaf and cinnamon [DOI]
- 49 Contact Dermatitis from Cinnamon [DOI]
- 50 Development of autoantibody responses in NC/Nga mice: its prevention by pulverized konjac glucomannan feeding [DOI]
- 51 The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma [DOI]
- 52 The treatment of atopic dermatitis with licorice gel [DOI]
- 53 Immune Pathways in Atopic Dermatitis, and Definition of Biomarkers through Broad and Targeted Therapeutics [DOI]
- 54 Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB [DOI]
- 55 Allergic contact dermatitis from fragrance components in specific topical pharmaceutical products in Belgium [DOI]
- 56 Anti-Allergic Effects of Vernonia amygdalina Leaf Extracts in Hapten-Induced Atopic Dermatitis-Like Disease in Mice [DOI]
- 57 Pathways to managing atopic dermatitis: consensus from the experts.
- 58 Moisturizers for Patients with Atopic Dermatitis: An Overview [DOI]
- 59 Clinical features of 31 patients with systemic contact dermatitis due to the ingestion of Rhus (lacquer) [DOI]
- 60 Dietary Oils and Phospholipids Containing n-3 Highly Unsaturated Fatty Acids Suppress 2, 4-Dinitro-1-fluorobenzene-induced Contact Dermatitis in Mice [DOI]
- 61 Inhibitory Effect of PG-Platycodin D on the Development of Atopic Dermatitis-Like Skin Lesions in ICR Mice [DOI]
- 62 A Noble Therapeutic Approach of Atopic dermatitis by Development of Th2 Chemokine Inhibitors from Natural Products : Inhibitory Effect of Sophora flavescens Extract in Atopic Dermatitis Model mice, NC/Nga
- 63 Efficacy of leaf extracts of Vernonia amygdalina Del. from central Africa on atopic eczema
- 64 Severe, chronic and recalcitrant atopic dermatitis associated with Tinea capitis: Diagnostic approach and effects of topical Vernonia amygdalina Del. extracts
Cited by 0
No indexed citations yet.
Related research
- Are Children Who Grow Up on Traditional Farms Protected From Asthma, Allergic Rhinitis and Allergic Sensitization? — shares topic coverage
- A Comparison of Mental Health Problems among Children with Alopecia Areata or Atopic Dermatitis and Their Parents — shares topic coverage
- Atopic Dermatitis among Children in Bamenda II, Cameroon: Prevalence and In-vivo Therapeutic Effects of Aqueous Extract of Cassia alata against DNCB Induced Atopic Dermatitis in Rats — shares topic coverage
- A Case Report and Review of Increased IgE in Patients with Transient Hypogammaglobulinemia of Infancy and Atopic Dermatitis after Normalization of IgG — shares topic coverage
- The Effectiveness of Combining Ipratropium Bromide and Salbutamol for the Treatment of Acute Severe Exacerbation of Asthma in Children: A Literature Review — shares topic coverage
Article metrics
Real usage data collected on this platform.
58
Page views
0
PDF downloads
11
Outbound clicks
0
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.