Incidence of Nosocomial Urinary Tract Infections and Antibiotic Susceptibility Pattern of Uropathogenic Bacterial Isolates of Patients from Selected Hospitals in Nsukka, Nigeria

Abstract

Urinary Tract Infection (UTI) is one of the significant healthcare and hygienic-based diseases ravaging millions of people, especially in third world countries with poor hospital settings. This cross-sectional and laboratory investigation was done to determine the incidence of nosocomial urinary tract infections (NUTIs) and antibiotic susceptibility pattern of the uropathogenic bacterial isolates from hospital patients in Nsukka, Southeastern Nigeria. Urine specimens of fifty patients were collected and analyzed between May and June 2018. Kirby-Bauer disk diffusion method was used for detection of antibiotic susceptibility pattern for all isolates. Bacteriuria was observed in urine specimens of 31 (62%) out of the 50 participants, with the specimens of 13 yielding significant growth at 42% rate of nosocomial urinary tract infections (NUTIs). The most predominant bacterial isolate of urinary tract infection was Staphylococcus spp. (31%); followed by Escherichia, Klebsiella and Proteus with (23%) each. Isolates were mostly susceptible to Ciprofloxacin (87.1%), while other isolates were mainly resistant to Zinnacef (937%). Pertinent recommendations were made with respect to treatment, multidrug resistance mitigation and aseptic and optimal health services delivery practices.