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Research Article Open access CC BY 4.0

Mucormycosis in Post COVID-19 Patients: A Case Study

Amitendra Shembekar, Ninad Nagrale, Nandkishor Bankar

Journal of Pharmaceutical Research International · pp. 233–239 · Published 15 Dec 2021

10.9734/jpri/2021/v33i58A34111

Abstract

Introduction: Acute respiratory distress syndrome (ARDS) is a common complication of severe pneumonia virus, such as the flu and COVID-19, which requires critical treatment, including asthma support, corticosteroids, and other treatments to prevent acute respiratory tract inflammation. Although steroid treatment is limited to the treatment of viral pneumonia, it is usually a double-edged sword, leading to increased morbidity and mortality. Mucormycosis is a fungal emergency with a high tendency for contaguous spread and a poor prognosis if not detected and treated promptly. Mucormycosis is believed to be caused by uncontrolled diabetes mellitus (DM) and other immunosuppressive disorders, such as corticosteroid therapy. Aim: To discuss causality factor of mucormycosis in COVID-19 infection. Conclusion: COVID-19 is correlated with a high rate of secondary infections, both bacterial and fungal, most likely as a result of immune dysregulation. Furthermore, the widespread use of steroids and broad-spectrum antibiotics as part of the COVID-19 remedy can result in the production or exacerbation of pre-existing fungal diseases. Physicians should be mindful of the likelihood of invasive secondary fungal infections in patients with COVID-19 infection, especially in those that have pre-existing risk factors, and should be able to detect and treat these infections early in order to reducing mortality and morbidity.

Mucormycosis Apophysomyces elegans immunosupression dm second-line fungal therapy corticosteroid therapy

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