Moringa oleifera Derived Phytochemicals against Shikimate Dehydrogenase of Helicobacter pylori Causing Peptic Ulcer
Sonali Suchismita Behera, Seema Suvadarshini, Truptimayee Chhotaray, Archita Sahoo, Subhadarshini Satapathy, Manasi Mohapatra, Bhagyeswari Behera, Srimay Pradhan
Journal of Pharmaceutical Research International · pp. 118–121 · Published 21 Jun 2020
10.9734/jpri/2020/v32i930540Abstract
Moringa oleifera plant extract is traditionally used to cure Peptic ulcer. It is caused by Helicobacter pylori. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 9-octadecenoic acid can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.
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