Rhamnose, A Safe Chemical Compound for the Manufacture of Immunostimulating Pharmaceuticals

Abstract

Introduction: Microorganisms such as bacteria, fungi, protozoa and viruses often cause irreparable damage to humanity. This is the case for diseases like black death, flu, AIDS, Ebola, Cholera, Mpox which have caused millions of deaths in the world. Plants and microorganisms contain carbohydrates like rhamnose which help boost the immune system. Some polysaccharide conjugate vaccines were manufactured to treat some pathogenic affections. Aim: The aim of this research is to use the literature to reassure scientists about the role that rhamnose could have in combating pathogenic diseases like immunology disorders. Methods: Electronic database engines such as Google Scholar, ScienceDirect, PubMed, Scopus, Biomed were used to carry out the work. Results: According to the researches, rhamnose (Rha or Rham) is mainly in nature in L form: L-rhamnose. It can be found as disaccharides, heteropolysaccharides and polysaccharides. It can combine with other chemical compounds. This could make the pharmacological activities of rhamnose more interesting and useful to the human organism in the case of immunological dysfunction. Its action repairs the damage caused by pathogens to the body and have used as active product for several studies. Rhamnose has highly an anti-inflammatory and antioxidant properties. Some vaccines have even been manufactured from L-rhamnose. Conclusion: Using rhamnose from any sources especially natural would be very beneficial for the search for effective vaccines, different from those already existing on the market and especially to undesirable effects tolerable for many people. Polysaccharides particularly rhamnose might be use for the manufacture of effective drugs and vaccines to prevent or cure immunodeficiency diseases.