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Research Article Open access CC BY 4.0

Metastatic Gist to the Ovary: A Case Report

Imane Chahbounia, Abdelkarim Poudiougou, Sofia El Omri, Imane Sella, Abdelkarim Antari, Faman Sano, Imad Taleb, Hamadoun Traoré, Mohammed Amine Saad, Khaoula Alaoui Slimani, Lamiaa Aalaoui, Saida Lamine, Adil Debbagh, Mohammed Reda Khmamouche, Choukri Elm’hadi, Tarik Mahfoud, Mohammed Anouar Mokhlis, Yassir Sbitti, Mohammed Ichou, Hassan Errihani, Rachid Tanz

Journal of Advances in Medicine and Medical Research · pp. 23–28 · Published 3 Feb 2026

10.9734/jammr/2026/v38i26064

Abstract

Background: Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasms of the gastrointestinal (GI) system. The most common sites of primary tumors are essentially the stomach and the small intestine. The secondary sites are the liver and the peritoneum. Materials and Methods: we report a rare case of metastatic GIST to the ovary. A 58-year-old female patient, was admitted to the emergency department for an obstructive syndrome. It was due to a small bowel obstruction, upstream of a right lateral uterine mass. Results: The anatomical-pathological study of the surgical specimen of the small intestine favored a GIST. A KIT mutation on the exon 11 was identified. The ovarian mass was also of tumor origin: a GIST. In the postoperative follow-up of this resected oligometastatic disease, imatinib was prescribed. Conclusion: metastatic gastrointestinal stromal tumors constitute half of GISTs. Several metastatic sites are possible; sometimes, they present in the form of Krukenberg tumors.  

Metastasis ovary GIST small intestine

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