Medicinal Plants Explain the Significant Role of Uric Acid for Malaria Parasite
Mosab Nouraldein Mohammed Hamad, Sufian Khalid M. Noor, Awadalla H Kashif, Mohammed Medani Eltayeb, Abdelgadir Elamin Eltom, Praveen Kumar Kandakurti, Elizabeth Popova, Shafie Abdulkadir Hassan, Yassin Bakri Salih, Tarig Mohammed Elfaki, Mohammed Ahmed Ibrahim Ahmed
Journal of Pharmaceutical Research International · pp. 13–18 · Published 13 Dec 2021
10.9734/jpri/2021/v33i55A33800Abstract
Medicinal plants, recognized and employed in conventional medicine practices since prehistoric era. Plants produce thousands of chemical substances for functions counting defence against insects, fungi, bacterial and parasitic diseases. Malaria is most widespread parasitic infection , it caused by coccidian protozoa of the genus plasmodium , four species are mostly infect human, P. falciparum, P. vivax, P. malriae and P. ovale, Majority of malaria cases resulted from P. falciparum and P. vivax. Uric acid regarded as one of the damaging molecular patterns of malaria parasite infection, and in this review we discussed the potential role of medicinal plants used as antimalarial to diminish the level of uric acid in gout patients. These may suggest that most of the complication associated with malaria, may attributed to amplified level of uric acid . Experimental studies recommended.
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