Measurement of Salivary Lipid Peroxidation in Periodontitis Patients with or Without Diabetes Mellitus
V. P. R. B. Ranjith Raj, M. Jeevitha, N. D. Jayakumar, Selvaraj Jayaraman
Journal of Pharmaceutical Research International · pp. 203–209 · Published 30 Dec 2021
10.9734/jpri/2021/v33i64A35320Abstract
Aim: The aim of the present study is to assess the association of lipid peroxidation in the saliva of healthy and periodontitis patients with or without diabetes mellitus. Study Design: Cross-sectional study. Materials and Methods: The study was conducted in the subjects who visited the University dental hospital as outpatients from October 2020 to January 2021.The subjects were categorized into 3 groups: periodontally healthy (Group a), Periodontitis with diabetes mellitus (Group b) and Periodontitis only (Group c) Results: Lipid peroxidation levels were found to be significantly higher (p<0.021 which is statistically significant) in patients with periodontitis and diabetes mellitus (108 + 7.1) when compared to patients with periodontitis only (77 + 3.5) and healthy group (66+5.6). Conclusion: The study concluded that lipid peroxidation levels are elevated in patients with periodontitis and diabetes mellitus compared to periodontitis only and also when compared to periodontal health which indicate that lipid peroxidation levels could serve as a biomarker for periodontitis in diabetic patients.
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