Prostate Specific Antigen Level in Diabetic Men at Bingham University Teaching Hospital, Jos, Plateau State, Nigeria

Abstract

The biomarker called Prostate Specific Antigen (PSA) is frequently employed for the early identification of prostate cancer. Numerous demographic, lifestyle, and health factors have been demonstrated to affect PSA levels in blood, therefore when interpreting test results, care should be taken to take these factors into consideration. The focus of this study is to evaluate the impact of Diabetes on PSA level in relation to their demographic characteristics. The study was conducted among 63 male subjects attending Bingham University Teaching Hospital (BHUTH). Subjects were classified into diabetic and non-diabetic groups (control group). The subjects who met the inclusion criteria were randomly selected and 3mls of blood was collected for PSA analysis using ELISA technique. In diabetic group, there was no significant difference in PSA level in each of the demographic parameters studied, p-value>0.05. In non-diabetic group, there was a significant difference in PSA level among the groups in Educational status, p-value=0.011 while other demographies did not report any significant change, p-value>0.05. There was no significant difference in PSA level between diabetic and non-diabetic groups, p-value>0.05. This study has shown Diabetes and demographic presentations have no effect on PSA level but educational status impacts on PSA level in normal individuals.