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Ngozi Brisibe

Publications (11)

Effect of Palm Kernel Oil on Plasma Sodium, Potassium and Chloride in Wistar Rats Induced with Febrile Seizures

Ngozi Brisibe, Ibioku Elekima, Holy Brown & Edna O. Nwachuku · Asian Journal of Medicine and Health · 2026

Background: Fever plays an important role in causing disturbances in fluid and electrolyte balance. Hyponatraemia has been thought to enhance susceptibility to seizures associated with febrile illnesses in childhood. Severe hyponatraemia and a non-significant increase in potassiu...

Open access Research Article 10.9734/ajmah/2026/v24i101437

Evaluation of Palm Kernel Oil on Some Pro-inflammatory Markers in Lipopolysaccharide and Kainic acid Seizures-Induced Wistar Rats

Ngozi Brisibe, Ibioku Elekima, Holy Brown & Edna O. Ibegbulem · Journal of Advances in Medicine and Medical Research · 2026

Background: Febrile seizures are common in early childhood and may involve measurable neuroinflammatory responses. Aims: This study evaluated whether palm kernel oil (PKO) modifies selected pro-inflammatory and damage-associated markers in Wistar rat pups exposed to lipopolysacch...

Open access Research Article 10.9734/jammr/2026/v38i76167

Tartrazine and Carmoisine Toxicity in Experimental Rats: A Systematic Review of Multi-Organ and Haematological Effects

Ibioku Elekima, Ngozi Brisibe & Adline E. Ben-Chioma · Asian Journal of Research in Biochemistry · 2026

Background: The study is a systematic review focusing on the tartrazine and carmoisine toxicity on renal, hepatic, pancreatic, glucose metabolism, and haematological indices in albino rats. Method: We systematically reviewed studies published using keywords and short medical term...

Open access Research Article 10.9734/ajrb/2026/v16i2482

Assessment of the Nephrotoxic Effect of Sodium Benzoate, Ascorbic Acid, and their Combined Administration in Albino Rats

Onengiyeofori Ibama, Ngozi Brisibe & Faithful Oluebube Lemoha · International Journal of Advances in Nephrology Research · 2025

Background: The increasing use of preservatives like sodium benzoate and vitamin C in food and beverages has raised concerns about potential health risks, including the formation of benzene, a carcinogenic compound. This study evaluated the nephrotoxic effect of sodium benzoate,...

Open access Research Article 10.9734/ijanr/2025/v8i169

Comparative Evaluation of Lipid Accumulation Product, and Triglyceride-Glucose Indices in Apparently Healthy Subjects in Predicting Cardiovascular Risks in Port-Harcourt

Eyindah Gloria Chimzindu, Ngozi Brisibe, Ibitoroko Maureen George–Opuda & Brown, Holy · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Lipid accumulation product is a novel biomarker of central lipid accumulation related to the risk of diabetes and cardiovascular diseases. In certain metabolic diseases, insulin resistance is often present which could be attributed to an abnormality in the insulin-specific recept...

Open access Research Article 10.9734/jamps/2023/v25i11652

Prostate Specific Antigen Level in Diabetic Men at Bingham University Teaching Hospital, Jos, Plateau State, Nigeria

A. I. Ekwempu, Ngozi Brisibe, D. B. Yakubu, N. Vwamdem & A. A. Onuigbo · Asian Journal of Research and Reports in Endocrinology · 2022

The biomarker called Prostate Specific Antigen (PSA) is frequently employed for the early identification of prostate cancer. Numerous demographic, lifestyle, and health factors have been demonstrated to affect PSA levels in blood, therefore when interpreting test results, care sh...

Open access Research Article

Assessing the Impact of Onion Juice on the Levels of Leutinizing Hormone and Follicle Stimulating Hormone in Female Mice Exposed to Transfluthrin Smoke

Helen Anthony Waribo, MaryJane Oluomachi Emenike & Ngozi Brisibe · Asian Journal of Medicine and Health · 2024

Aim: Transfluthrin is a fast-acting insecticide used in household mainly against mosquites. Its uses have not been without health risk to humans. The study aims at evaluating the effect of onion juice on follicle stimulating hormone and leutinizing hormone levels in mice exposed...

Open access Research Article 10.9734/ajmah/2024/v22i61034

Alterations in Hepatocellular, Reproductive, and Oxidative Stress Parameters in Female Albino Rats Exposed to Crude Oil

Ibioku Elekima, Thankgod Prince Ohaka, Ngozi Brisibe, Adline Ben-Chioma, Ibitoroko George-Opuda, Orbenyie Mary Festus, Ani Precious Onyinyechi & Waribo Helen Anthony · International Journal of Biochemistry Research & Review · 2022

Aim: To study the effect of exposure to crude oil on the liver, ovary, and some oxidative stress parameters in albino rats. Study Design: A total of 50 female albino rats were used in the experiment. The rats were grouped into three: The control group which consisted of 10 rats,...

Open access Research Article 10.9734/ijbcrr/2022/v31i10783

Hepatocellular Recovery of Chronic Paraquat Induced Liver Toxicity in Vitamin E and C Treated Male Wistar Rats

Benjamin Nnamdi Okolonkwo, Adaobi Ifeoma Ekwempu, Ngozi Brisibe, Joel Burabar Konne & Clement Ugochukwu Nyenke · International Journal of Biochemistry Research & Review · 2022

Paraquat is an organic compound also known as methyl viologen, a chemical herbicide or weed killer with highly toxic effect on ingestion or exposure. Vitamin E and C are powerful antioxidants that act as initial responder against oxygen reactive species called free radicals which...

Open access Research Article 10.9734/ijbcrr/2022/v31i730334

Evaluation of Protective Properties of Elaeis oleifera Fruit Extract on Renal Parameters of Dichlorvos-Induced Nephrotoxocity in Albino Rats

Edna Ogechi Nwachuku, Fedelis Beega, Adline Erinma Ben- Chioma, Ngozi Brisibe & Ibioku Elekima · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aim: Evaluate the protective effects of palm oil on renal parameters after dichlorvos toxicity in albino rats. Study Design and Methodology: The study consisted of 3 phases: The acute study which lasted for 24 hours, the sub-acute study which lasted for 14 days and the sub chroni...

Open access Research Article 10.9734/jamps/2020/v22i630175

Evaluation of Some Biochemical Parameters in Printers Occupationally Exposed to Large-format Printing Machines in Port Harcourt, Nigeria

Donatus Onukwufor Onwuli, Onengiyeofori Ibama, Otenobebi Ramoni, Elekima Ibioku, Adline Erinma Ben-Chioma, Helen Anthony Waribo & Ngozi Brisibe · Journal of Advances in Medicine and Medical Research · 2024

Ensuring occupational health and safety is crucial across diverse industries, and the printing sector is no exemption. Workers operating large format printing presses are exposed to printing inks and materials containing potentially hazardous chemicals and solvents. This case-con...

Open access Research Article 10.9734/jammr/2024/v36i65460