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Research Article Open access CC BY 4.0

Impact of Delay in Immune Response Activation on HIV Infection Dynamics

Mehdi Maziane, El Mehdi Lotfi, Khalid Hattaf, Noura Yousfi

Journal of Advances in Mathematics and Computer Science · pp. 1–15 · Published 4 Apr 2017

10.9734/BJMCS/2017/30819

Abstract

In this work, we propose an HIV infection model with cure of infected cells in eclipse stage and delay in the activation of immune response. The stability of the equilibria and the existence of the Hopf bifurcation are investigated. Moreover, numerical simulations are carried out to illustrate our theoretical results.

HIV infection CTL immune response delay hopf bifurcation.

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