Sclerodermatomyositis Overlap Syndrome with Bullous Lesion: A Rare Presentation

Abstract

Overlap syndrome is diagnosed when at least two classical connective tissue diseases are observed in one patient, which develops simultaneously or sequentially. Sclerodermatomyositis (SDM) is one of the overlapping syndromes, defined by the association of dermatomyositis and scleroderma, which may be localized or systemic. The American College of Rheumatology European League against Rheumatism (ACR-EULAR) classification criteria are used to establish the diagnosis of systemic sclerosis and dermatomyositis. Clinically, this syndrome is characterized by the association of myalgia or myositis, arthralgia, with the skin changes of scleroderma, as well as Raynaud's phenomenon, interstitial lung disease, calcinosis, masked facies, dysphagia or esophageal dysmotility4, and immunologically, the presence of specific Pm/Scl antibodies in over 50% of cases. Rare cases in the literature have described this association, but not in its bullous form, which is why we report here on a patient with bullous sclerodermatomyositis.