Background: Anhidrotic ectodermal dysplasia (AED), also referred to as hypohidrotic ectodermal dysplasia, is a rare genetic condition characterized by a triad of hypotrichosis, hypodontia, and hypohidrosis. Case Report: This article reports two illustrative cases: an adolescent a...
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Research Article10.9734/ajpr/2025/v15i7467
Background: Congenital ichthyoses are rare genetic skin disorders characterized by abnormal keratinization, often present at birth and associated with various extracutaneous manifestations. Material and Methods: We conducted a retrospective 30-month study at a Moroccan university...
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Research Article10.9734/ajpr/2025/v15i7464
Background: Cutaneous mastocytosis (CM) is a rare pediatric dermatosis characterized by the abnormal proliferation and accumulation of mast cells in the skin. It typically presents in early childhood and is most often confined to the skin, with a generally favorable prognosis. Ma...
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Research Article10.9734/ajpr/2025/v15i7463
Pressure alopecia is a rare and often underrecognized form of hair loss caused by prolonged ischemia of the scalp. Frequently misdiagnosed, it requires a high index of suspicion and a careful clinical and dermoscopic assessment. Trichoscopy plays a pivotal role in its diagnosis....
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Research Article10.9734/ajrdes/2025/v8i1133
Aims: Hay–Wells syndrome (ankyloblepharon–ectodermal dysplasia–clefting or AEC syndrome) is a rare autosomal dominant disorder caused by TP63 mutations, classically associated with skin, hair, nail, and craniofacial anomalies. Although hair abnormalities are commonly reported, th...
Open access
Research Article10.9734/ajpr/2025/v15i6455
Background: H syndrome is a rare autosomal recessive, multisystem non-Langerhans cell histiocytosis associated with biallelic pathogenic variants in SLC29A3. Published data from North Africa remain limited, and phenotypic variability may complicate clinical recognition. Case Pres...
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Research Article10.9734/ajrdes/2026/v9i1165
Background: Bullous erythema multiforme (EM) major is an uncommon mucocutaneous disorder, and its association with Parvovirus B19 is exceptionally rare. This report describes an immunocompetent adult with Parvovirus B19 DNA detected locally in blister fluid after common infectiou...
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Research Article10.9734/ajrdes/2026/v9i1163
Background: Desmoplastic trichoepithelioma (DTE) is a rare, benign adnexal tumor derived from follicular germinative cells. It predominantly affects young females and commonly presents on the face as annular plaques or papules with a depressed center. The tumor poses diagnostic c...
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Research Article10.9734/ajrdes/2025/v8i1135
Castleman disease is a rare lymphoproliferative disorder, particularly in children. Its association with pityriasis lichenoides has not been previously reported. This report presents a 5-year-old girl born to consanguineous parents, who developed recurrent necrotic and bullous sk...
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Research Article10.9734/ajpr/2025/v15i7462
Introduction: Eosinophils, play major roles in the pathogenesis of various dermatoses (atopic dermatitis, bullous pemphigoid, drug reaction with eosinophilia and systemic symptoms (DRESS)…). Hypereosinophilia in pemphigus has not been well documented in the literature, hence we i...
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Research Article10.9734/ajrdes/2024/v7i1104
Introduction: Pemphigus is a group rare heterogeneous of intraepidermal autoimmune chronic bullous dermatoses associated with a high risk of morbidity and mortality. Despite its rarity, this condition persists as the most prevalent among bullous dermatoses in the Maghreb, includi...
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Research Article10.9734/ajrdes/2024/v7i1101
Introduction: Psoriasis is an immune cell-mediated inflammatory skin disease, characterized by the formation of scaly, indurated, erythematous plaques. Psoriasis comorbidities and symptoms affect the choice of treatments. Secukinumab is a fully human monoclonal anti-body that sel...
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Research Article10.9734/ajrdes/2024/v7i1100
Introduction: Dermatological emergency is defined as any acute dermatological disorder that develops and worsens in less than 5 days. Aims of Study: The aim of our study is to identify the main dermatological emergencies consultations, establish a demographic and clinical profil...
Open access
Research Article10.9734/ajrdes/2024/v7i199
Aims: Folliculotropic mycosis fungoides (FMF) is an uncommon variant of mycosis fungoides, rarely described in children. This type of lymphoma is particularly unresponsive to treatment and has a poor prognosis. Paradoxically, it can be clinically confused with conditions as benig...
Aims: To describe a rare case of paraneoplastic pemphigus (PNP) occurring in a patient with synchronous pulmonary and gastric mucosa-associated lymphoid tissue (MALT) lymphoma and to summarise the diagnostic and therapeutic considerations documented in this case. Presentation of...
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Research Article10.9734/ajrdes/2026/v9i1166
Narjess Er-rachdy, Ouissal Essadeq, Maha Habibi, Taha Aaboudech, Kaoutar Znati, Laila Benzekri & Nadia Ismaili·Asian Journal of Pediatric Research·2025
Background: Giant congenital melanocytic nevus (GCMN) are rare pigmented lesions present at birth, often exceeding 20 cm in size, and may be associated with serious complications such as melanoma and neurocutaneous melanosis. Neurofibromatosis type 1 (NF1) is a common phakomatosi...
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Research Article10.9734/ajpr/2025/v15i8466
Background: Hidradenitis suppurativa (HS) and psoriasis are chronic inflammatory diseases that may coexist and share IL-17–mediated pathogenic pathways. Secukinumab, an anti–IL-17A monoclonal antibody, is effective in psoriasis and has shown promise in HS. Case report: We report...
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Research Article10.9734/ajrdes/2025/v8i1134
Ouissal Essadeq, Narjess Er-rachdy, Meriem Boubekri, Taha Aaboudech, Kaoutar Znati, Laila Benzekri & Nadia Ismaili·Asian Journal of Pediatric Research·2025
Background: Lichenoid mycosis fungoides is an exceptionally rare entity in children, often posing significant diagnostic challenges due to its atypical presentation and resemblance to benign dermatoses. Case Report: We report a pediatric case of lichenoid mycosis fungoides presen...
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Research Article10.9734/ajpr/2025/v15i6457
Overlap syndrome is diagnosed when at least two classical connective tissue diseases are observed in one patient, which develops simultaneously or sequentially. Sclerodermatomyositis (SDM) is one of the overlapping syndromes, defined by the association of dermatomyositis and scle...
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Research Article10.9734/ajrdes/2024/v7i1106
Capillary malformation and Bowen's disease (BD) or intraepidermal squamous cell carcinoma are two different entities whether clinically, histologically or prognostically. Bowen’s disease or squamous cell carcinoma in situ is a precursor malignant neoplasm restricted to the epider...
Open access
Research Article10.9734/ajrdes/2024/v7i1102
Chourouq Mustapha Eid, Fatima Ezzahraa Sassine, Manal El Beyeg, Taha Yassine Aaboudech, Kaoutar Znati, Narjess Er-rachdy, Laila Benzekri & Mariame Meziane·Asian Journal of Research in Dermatological Science·2026
Aims: To report a case of Hailey-Hailey disease identified with the aid of dermoscopy in a woman with a darker skin phototype whose chronic flexural intertrigo had repeatedly been misdiagnosed and treated as a fungal infection, and to highlight dermoscopic features that may reduc...
Open access
Research Article10.9734/ajrdes/2026/v9i1173
Background: Generalized Bullous Fixed Drug Eruption (GBFDE) is a severe cutaneous adverse drug reaction that can mimic toxic epidermal necrolysis (TEN). Its prompt recognition is crucial to prevent severe complications and recurrence upon drug re-exposure. Case Report: We report...
Open access
Research Article10.9734/ajrdes/2025/v8i1123
Chourouq Mustapha Eid, Fatima Ezzahraa Sassine, Taha Yassine Aaboudech, Kaoutar Znati, Sarah LOUBARIS, Hafsa Riache, Latifa Chat, Laila Benzekri & Mariame Meziane·Asian Journal of Research in Dermatological Science·2026
Aims: To report an exceptional case of scalp sarcoidosis revealing systemic sarcoidosis and to underline the contribution of trichoscopy to the diagnosis. Presentation of Case: A 50-year-old Moroccan woman with multinodular goitre presented with a chronic, non-pruritic, painless...
Open access
Research Article10.9734/ajrdes/2026/v9i1172
The teeth, skin, hair, nails and eccrine and sebaceous glands which are tissues ectodermally or mesodermally derived can be affected by rare disorders called ectodermal dysplasias. The most common type of ectodermal dysplasias is known as Christ-Siemens-Touraine syndrome or anhid...
Open access
Research Article10.9734/ajrdes/2025/v8i1120
Marwa Asermouh, Chaimae Ait Khabba, Sektaoui Soukaina, Sabrine Derqaoui, Znati Kaoutar, Mariame Meziane, Nadia Ismaili, Laila Benzekri & Karima Senouci·Asian Journal of Research in Dermatological Science·2023
Aims: The reported association of Plummer-Vinson syndrome and some autoimmune diseases, including pemphigus -association described for the first time-, raises the hypothesis of the autoimmune origin of this syndrome. On the other hand, this unexpected association represents a the...