Metal Complexes of Gatifloxacin: Synthesis, Characterization and Evaluation of Biological Activity
Asian Journal of Chemical Sciences · pp. 98–107 · Published 21 Dec 2021
10.9734/ajocs/2021/v10i419109Abstract
The antibiotic agent Gatifloxacin is well known for its drug design and coordinating ability towards metal ions. In this paper, synthesis and biological activity of Mn(II), Co(II), Ni(II), Cu(II) and Mg(II) complexes of gatifloxacin is reported. Ligand is itself prepared using o-phenylenediamine (OPD) and 3-acetyl coumarin. The structure of complexes has been investigated using some physiochemical and spectroscopic techniques. In vitro evaluation of these complexes was also carried out for antibacterial and antimicrobial activity. Some complexes exhibited promising anti-bacterial and antimicrobial activity compared to gatifloxacin drug.
Cited by 0
No indexed citations yet.
Related research
- Evaluation of Phytochemical Constituents and Antimicrobial Activity of Leaves and Stem Bark Extracts of Sarcocephalus latifolius — shares topic coverage
- Diversity and Antimicrobial Activity of Hydrobionts Associated Microorganisms from the Sea of Japan with the Occurrence of Tropodithietic Acid Producing Bacteria — shares topic coverage
- Antimicrobial Activity of Emilia pratermissa Leaf Extracts on Organisms Isolated from Patients with Otitis Media Attending Federal Medical Centre Owo and Ondo States Specialist Hospital Akure — shares topic coverage
- Molecular Identification, Bioactivity Screening and Metabolic Fingerprinting of the Actinomycetes of Chenab River Sediments — shares topic coverage
- Evaluating Efficacy of Biosurfactants from Bacterial Isolates in Conferring Protection against Rhizoctonia and Sclerotium Infection in Wheat and Peanut Plants — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.