Coronavirus Disease (COVID-19): Pathogenicity, Transmission, Epidemiology, Diagnosis, Case Management and Public Health Response

Abstract

The spread of Coronavirus Disease 2019 (COVID-19) to almost every part of the globe making it a global pandemic as resulted to be a global crisis with urgent need of innovative research ideas, mechanisms and strategy to treat, curtail, contain and prevent the spread of the disease. Covid-19 caused by a novel virus SARS-CoV-2. Leaders around the world have being engaging researchers and scientists for possible vaccine for COVID-19. This pandemic has caused instability in social, economy and psychological balance around the world which has resulted to a new way of life (new normal) which might not return to former normal soon. COVID-19 was declared as a global health emergency that poses threat to humanity, hence, it becomes imperative to abridge and ameliorate its effect, as we await the flattening of the pandemic curve and vaccine development. This review summarizes and provides meaningful information for recent and future research related to the viral origin, epidemiology, transmission, pathogenicity, clinical manifestation and diagnosis, management, prevention and control of coronavirus. All countries in the world and all concerned stakeholders should increase the awareness and provide necessary strategies holistically at the community, state, region, national and international levels to combat this disease.