Hypoglycemic and Hypolipidemic Potentials of Extract of Vernonia calvoana on Alloxan-Induced Diabetic Albino Wistar Rats
I. A. Iwara, G. O. Igile, F. E. Uboh, E. U. Eyong, P. E. Ebong
European Journal of Medicinal Plants · pp. 78–86 · Published 17 Apr 2015
10.9734/EJMP/2015/16058Abstract
Objective: Investigations were carried out to evaluate the therapeutic potentials of extract of Vernonia calvoana as herbal medicines. Methods: In this study, the hypoglycemic and hypolipidemic potentials of extract of Vernonia calvoana was evaluated by using normal and alloxan-induced diabetic rats at a dose of 400 mg/kg b.w. daily for 14 days. Fasting Blood glucose levels and body weight were monitored at 7 days intervals, and different biochemical parameters, serum glucose, serum cholesterol, serum triacylglycerol, high density lipoprotein, low density lipoprotein and very low density lipoprotein were also assessed in the experimental animals. Results: It was found that extract of Vernonia calvoana showed significant hypoglycemic and hypolipidemic activity (P<0.01). Conclusion: Extracts of Vernonia calvoana showed significant hypoglycemic and hypolipidemic activity, which provides the scientific proof for their traditional claims.
Cited by 11
Ariane T. Mbemi, Jennifer N. Sims, Clement G. Yedjou · International Journal of Molecular Sciences · 2020
Abdisa Tagesu · Journal of Veterinary Medicine and Animal Health · 2018
Iwara Arikpo Iwara, Victor S. Ekam, Eve O. Mboso · Beni-Suef University Journal of Basic and Applied Sciences · 2023
Godwin Egbung, Item Atangwho, Ochuole Odey · Medicines · 2017
Arikpo Iwara Iwara, Oju Igile Godwin, Effiong Uboh Friday · Journal of Pharmacognosy and Phytotherapy · 2017
Adegbolagun T. Adeoye, Ademola A. Oyagbemi, Aduragbenro D. Adedapo · Journal of Medicinal Plants for Economic Development · 2017
Godwin Eneji Egbung, Ochuole Diana Odey, Item Justin Atangwho · Asian Journal of Biochemistry · 2017
O. Obinna Uchewa, O. Joseph Ezugworie · Journal of Trace Elements in Medicine and Biology · 2019
I. A. Iwara, G. O. Igile, O. E. Mboso · African Journal of Pharmacy and Pharmacology · 2017
Ubana Eyong Eyong, Eneji Egbung Godwin, Ndubuisi Ndiodimma Victor · Journal of Pharmacognosy and Phytotherapy · 2018
Related research
- Comparative Effects of Fermented and Unfermented Parkia biglobosa Bean Seeds in Diabetic Induced Experimental Rats — shares topic coverage
- Hypoglycemic, Hematologic and Hypolipidemic Activity of Mucuna Pruriens Ethanol Leaf Extract in Alloxan Induced Diabetic Rats — shares topic coverage
- Hypoglycaemic and Hypolipidaemic Effects of the Aqueous Leaf Extracts of Tithonia diversifolia — shares topic coverage
- Hypoglycemic, Antihyperlipidemic and Antioxidant Effects of Manniophyton fulvum Aqueous Root Extract on Streptozotocin-induced Hyperglycemic Wistar Rats — shares topic coverage
- The Effect of Aqueous Extract of Buchholzia coriacea Seeds on Some Biochemical Parameters in Normal and Alloxan-induced Diabetic Rats — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
11
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.