Isolation of Chemical Constituents and Invitro Antidiabetic Activity of Mirabilis Jalapa Flower Extracts
Deepth D. Kodical, Jennifer Fernandes, Jane Mathew, K. Deepthi, K. Vijay Bhaskar
Journal of Pharmaceutical Research International · pp. 412–419 · Published 20 Dec 2021
10.9734/jpri/2021/v33i60A34501Abstract
Objectives: The present work was designed to investigate the phytochemical and in vitro screening of the flower extracts of Mirabilis jalapa. Materials and Methods: Phytochemical constituents were isolated using column chromatography and characterized of the compounds were carried out using IR, 1H NMR, 13C NMR and mass spectroscopy data. In vitro anti-diabetic activity was evaluated by alpha-amylase inhibition assay and Alpha-glucosidase inhibition assay. Results: Phytochemical investigation of the ethanol extract revealed the presence of a flavonoid Kaempferol and a triterpenoid Lupeol. In vitro investigation indicated that the Mirabilis jalapa flowers extracts has considerable anti-diabetic activity Conclusion: The anti-diabetic activity may due to the presence of phytoconstituents like flavonoids, triterpenoids, steroids.
Cited by 2
Jia-Huan Ke, Ren-Bo An, En-Ji Cui · Biochemical Systematics and Ecology · 2022
Showing 1 of 2 known citations — external sources report more than can currently be individually listed.
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