Invasive Hemifacial Mycosis Mimicking Facial Malignancy: A Case Report
Oshiozimede Quincy AIGBONOGA, Oluwafemi Olasupo AWE, Orume Lucky ENEGBUYA, Kerry AZEKE, Stella Nneka NGWU, Ewoigbe IKHUORIA, Charles IKHIFA, Fidelis OZOBA, Miracle Onosetale EDOKPA, Unity Akugbe EHIJIE
Asian Journal of Case Reports in Surgery · pp. 401–406 · Published 7 Jul 2025
10.9734/ajcrs/2025/v8i2656Abstract
Invasive facial fungal infections are confusing disease processes that can involve one, or more regions of the face, presenting with varied clinical features that mimic other clinical conditions that could range from benign disease conditions to malignancies. While typically exhibiting characteristic features of fungal disease, facial mycosis can sometimes present in an unusual manner, having improbable localization to different aspect of the face such as the eyelids, cheeks, ear, etc. We present a 75-year-old retired military man from the rural part of southern Nigeria who presented with left hemifacial growth and deformity, and ptosis of the left upper eyelid. Tissue biopsy analysis yielded Histoplasmosis which when treated with the use of oral and topical anti-fungal medications led to complete resolution of all presenting complaints.
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