Skip to content
Research Article Open access CC BY 4.0

Intracranial Pleomorphic Malignant Fibrous Histiocytoma, Associated to Systemic Lupus Erythematous: A Case Report

Martha Lilia Tena-Suck, Carlos Sánchez-Garibay, Citlaltepelt Salinas-Lara

Journal of Advances in Medicine and Medical Research · pp. 1–8 · Published 30 May 2017

10.9734/BJMMR/2017/32743

Abstract

Background: Pleomorphic Malignant Fibrous histiocytoma (MFH) is a rare neoplasms of the soft tissue and bone composed of fibroblastic and histiocytic components with mitosis figures, nuclear pleomorphism and anaplasia. Case Presentation: We presented a rare case of MFH in 44 year old woman with history of systemic erythematosus lupus and seizures. Treated with prednisone. The cerebral TAC showed a temporal mass. Craniotomy was performed and the examination of the biopsy sample revealed a giant, pleomorphic and atypical cells. Immunohistochemical analysis showed positivity for vimentin, CD68, Fascin, lysosyme and MIB-1 labeling index of 20%. Pleomorphic malignant fibrous histiocytoma was diagnosed, with involvement of the overlying temporal lobe. We report a case of MFH of the left temporal in adult.  Discussion: The neuroimaging and intra-operative opinion were of a meningioma. Histopathology, in conjunction with immunohistochemical evaluation and proliferation marker, confirmed the diagnosis. This is the firth case reported of PMFH associated to systemic lupus erythematous and different histological patterns.

Brain tumors primary intracranial fibrous histiocytomas pleomorphic malignant fibrous histiocytoma immunohistochemistry

Cited by 0

No indexed citations yet.

Article metrics

Real usage data collected on this platform.

0

Page views

0

PDF downloads

0

Outbound clicks

0

Citations

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

No views recorded yet.

Traffic sources

Referring site, by host.

No traffic recorded yet.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.